Investigations Flashcards
what bloods should be done for haematology
FBC & Coags
what bloods check biochemistry
U&Es, LFTs, Ca, Glucose, amylase/lipase, CRP & Lactate
what amylase result is diagnostic?
> 3 times upper limit of normal
what are 2 serum transaminases?
ALT & AST
what do serum transaminases show
hepatocyte injury
where does alkaline phosphate show damage to?
bone and liver
what is the main marker for liver and cholestatic disease?
gamma glutamyl transferase (Gamma GT)
what does gamma GT aid the diagnosis of?
whether raised ALP indicates liver or bone damage
what are the 3 indices of synthetic functionality of liver?
albumin, prothrombin time and bilirubin
why does a raised prothrombin time suggest issues with liver synthetic functionality?
liver synthesises most clotting factors so long prothrombin time = damage to liver
what is endoscopy used for?
diagnosis, tx, screening and surveillance
what can endoscopy help diagnose?
ulcers, tumours, vascular pathology, stones, worms etc
what are 2 endoscopic diagnosis sub-techniques?
dye staining
microscopy
biopsy=
histology (cell structure)
brushing=
cytology (cell function)
what therapeutic techniques can endoscopy be used for?
GI bleeding, foreign body, resection of cancer, strictures
what can endoscopy do if a GI bleed occurs?
banding, glue, clips, injection therapy
what can endoscopy do for strictures?
balloon insertion, stenting
what can endoscopy do for tumours?
polypectomy, endoscopic mucosal removal
what does endoscopy screen for?
cancer
what object is used to survey UC, colonic polyps, Barrett’s O?
endoscope
what is MRCP commonly used to investigate?
common bile duct pathology
what is ERCP commonly used to investigate?
pancreatic and bile duct pathology
what radiological technique is used for cholecystitis?
USS then MRCP or ERCP