Introduction to the Endocrine System Flashcards
Chemicals that act locally at the site of synthesis (do not travel to distant sites) are….
paracrine
chemicals that act on the same cell that synthesises the hormone (eg cytokines) are……
autocrine
chemical that are released from exocrine glands via ducts to the external environment are …..
exocrine
neuro hormones are released from…… and then they enter blood and travel to their target cells
nerves
insulin acts on the liver and increases…. and decreases…..
glycogenesis
gluconeogenesis
cells that secrete chemical that bind to receptors on the same cell act in response to …….. signals
autocrine
Chemicals diffuse in ECF to affect the neighbouring cells are in response to …… signals
paracrine
endocrine hormones have their action terminated - often via…. ….. ….
negative feedback loops
peptide (or protein) hormones are composed of
chains of amino acids
these are the most common type of hormone
Amine hormones are derived from
one of 2 amino acids
what are the 2 amino acids that amine hormones come from?
tyrosine and tryptophan
Steroid hormones are derived from
cholesterol
3 examples of peptide hormones
FSH
TRH
insulin
Peptide hormones are synthesised as
preprohormones
then prohormones that are kept in vesicles til use
Measuring inactive fragments in plasma can be useful clinically - give an example used in diabetes
C-peptide
what is C-peptide?
the inactive fragment from the insulin prohormone