Immunology of endocrine (finish when revising) disease

Question 1

Are autoimmune diseases more common in males or females?

Answer 1

females

Question 2

What autoimmune disorder would result from attacking the self-antigen ACH receptor?

Answer 2

Myasthenia Gravis

Question 3

What autoimmune disorder would result from attacking the self-antigen TSH receptor?

Answer 3

hypo or hyperthyroidism

Question 4

tolerogens

Answer 4

antigens that induce tolerance

Question 5

What type of diabetes is insulin dependent?

Answer 5

T1DM

Question 6

What do delta cells in the islets of langerhans secrete?

Answer 6

somatostatin (GHIH)

Question 7

What do beta cells in the islets of langerhans secrete?

Answer 7

insulin

Question 8

What do alpha cells in the islets of langerhans secrete?

Answer 8

glucagon

Question 9

causes of T1DM

Answer 9

viral infections

genetic factor

autoimmune

Question 10

What type of diabetes involves the lymphocytic infiltration of islet of langerhans with specific destruction of beta cells?

Answer 10

T1DM

Question 11

suspected diabetes:

normal or high insulin levels.

What type of diabetes do they have?

Answer 11

T2DM

Question 12

Juvenile onset diabetes

Answer 12

type 1

Question 13

Thyroid gland:

What lines their cuboidal cells?

Answer 13

follicles

Question 14

hyperthyroidism 3 main causes:

Answer 14

graves disease

functioning adenoma

toxic multi nodular goitre

Question 15

most common cause of thyrotoxicosis

Answer 15

graves disease

Question 16

LATS are common in

Answer 16

graves disease

Question 17

what are LATS?

Answer 17

long acting thyroid stimulating immunoglobulins

Question 18

most common cause of hypothyroidism

Answer 18

hashimoto’s thyroiditis

Question 19

cretinism can be a result of what?

Answer 19

congenital hypothyroidism