Intro To Medical Mycology Flashcards
Example of multicellular
Molds
Example of unicellular
Yeast
Fungi doesn’t have cell wall or peptidoglycan, instead they have
Chitin
What is heterotrophs
Unable to make their own food
Fungi loves
Oil surfaces
Cell membrane of fungi has —— that is targeted by the anti fungal treatment
Ergosterol
Fungal form
-mushroom (macro organism)
-Yeast (unicellular
-molds (multicellular)
Medically important fungi
-Basidiomycota
-Zygomycota
-hyaline hyphomycete
-Dematiaceous hyphomycete
-Ascomycota
True or false: There are 1.5 million species of fungi and 300 of those are medically important
True
True or false: Antibiotic can’t kill fungi
Yes because fungi doesn’t have cell wall or peptidoglycan
-fast growing and characterized by primitive coencytic hyphae -mostly aseptate (no division)
-causes acute and fulminant opportunistic systems mycoses in immunosuppressed and acidotic diabetes px
Zygomycetes
Medically important zygomycetes
- Entomophthorales : subcutaneuos zygomycosis
- Mucorales : subcutaneous and systemic zygomycosis
Subcutaneous zygomycosis
Entomophthorales
Example of entomophthorales (subcutaneous zygomycosis)
-Basidiobolus and condiobolus
Subcutaneous and systemic zygomycosis
Mucorales
Example of mucorales (subcutaneous and systemic zygomycosis)
Mucor and rhizopus
Structure of rhizopus spp
Rootlike
Mucor spp when mature it has
Sporangia
2 types of hyphae
Aseptate and septate
Has no division
Aseptate
Has division
Septate
Fungi that has a potential of being systemic pathogens
Basidiomycetes
Medically important basidiomycetes
- Basidiomycetes yeast
- Mushrooms
Example of basidiomycetes yeast (medically important basidiomycetes)
Cryptococcus neoformans and cryptococcus gattii
Microscope use in observing cyrptococcus neoformans
Dark field microscopy
Stain used in observing the capsule of cryptococcus neoformans
India ink
Saprobes
Characterized by septate hyphae with simple spores
Asexual reproduction by condidia
Sexual reproduction by ascospores
Asci are often housed in a fruiting body
Ascomycota
Medically important ascomycota
- Pseudallescheria and eurotium spp
- Leptosphaerian and neotestudina - agent of mycetoma
- Piedraia hortae - black piedra
Agent of mycetoma
Leptosphaeria and neotestudina
Location of asci
Inside the ascospore
A class of fungi where most of the Medically important member belongs to
Fungi without fruit bodies
Differentiated by macroscopic and microscopic characteristics
Hyphomycetes
Hyphomycetes is differentiated mainly by
Macroscopic and microscopic characteristics
Medically important hyphomycetes
- Dermatophytes
- Aspergillus spp.
- Dimorphic fungi
- Dematiaceous fungi - color brown
Most common isolated aspergillus spp.
Aspergillus fumigatus
Microsporum gypseum
Dermatophyte
Growth temp of yeast
Body temp 37degrees C
Growth temp of molds
Body temp 20-25degrees C
Has yeast and molds form
Dimorphic fungi
Human fungal infection
Mycoses
Study of fungi that impacts human health
Medical mycology
Dimorphic fungi
Histoplasma capsulatum
Dematiaceous fungi (color brown)
Curvalia spp
Types of mycoses
- Superficial mycoses
- Cutaneous mycoses
- Subcutaneous mycoses
- Systemic mycoses
Type of mycoses that the fungal infection involving inly the skin and or hair
Superficial mycoses
Type of mycoses that the fungal infection involving only the skin, hair and nail
Cutaneous mycoses
Type of mycoses that chronic localized infection of the skin and subcutaneous tissue following traumatic implantation of causative agent
Different type of systemic mycoses
- Dimorphic systemic mycoses
- Opportunistic systemic mycoses
Type of systemic mycoses that the fungal infection of the body is caused by geographically restricted fungal infection
Dimorphic systemic mycoses
Usual site of infection in dimorphic systemic mycoses
Pulmonary following the inhalation of conidia
Type of systemic mycoses that the fungal infection of the body which occur almost exclusively among immunocompromised px
Opportunistic systemic mycoses
Common example of opportunistic systemic mycosesn
Candida albicans