Intestine Flashcards

1
Q

increase in surface area ?

A

microvilli
villi
plicae circulares

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2
Q

microvlli

A

cytoplasmic projections of cell membrane

striate border of simple columnar epithelium

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3
Q

villi

A

evaginations of mucosa with core of lamina propria
-distinguishing characteristic of small intestine

multicellular structures

exclusively in small intestine

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4
Q

villi in duodenum

A

broad, short, leaf like

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5
Q

villi in jejunum

A

tongue-like projections

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6
Q

villi in ileum

A

all, narrow, finger like projections

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7
Q

plicae circulares

A

circular folds of entire mucosa, with core of submucosa**

permanent projections into lumen

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8
Q

where do plicae circulares begin?

A

proximal duodenum

maximized in distal duodenum and proximal jejunum

diminish until absent in distal half of ileum

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9
Q

exocrine glands

A

pancreas

liver

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10
Q

submucosal glands

A
duodenal glands (brunners glands)
-in submucosa of duodenum

secrete mucous

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11
Q

brunners glands

A

duodenal submucosa glands

secrete slightly basic mucous

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12
Q

small intestine

A

submucosa has basic mucous producing

-to neutralize the acidic stomach content

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13
Q

liver excretion

A

bile - to emulsify fats

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14
Q

pancreas excretion

A

enzymes primarily in peptide degradation

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15
Q

intestinal crypts

A

mucous secreting glands in small intestine

-epithelium invaginations into lamina propria in small and large intestine

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16
Q

epithelium of small intestine

A

simple columnar epithelium replaced every 3 to 7 days

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17
Q

cell types in epithelium of small intestine

A
absorptive columnar cells
goblet cells
lymphocytes
enteroendocrine cells
paneth cells
M cells
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18
Q

goblet cells

A

secretes mucous

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19
Q

as we move down GI tract?

A

number of goblet cells increase

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20
Q

enteroendocrine cells in epithelium of small intestine?

A

mainly in crypts

  • rarely in villus
  • secrete products into vasacular channels in lamina propria
21
Q

K-cells

A

secrete incretins

enteroendocrine cell of small intestine epithleium

22
Q

L-cells

A

secrete GIP

enteroendocrine cell of small intestine epithelium

23
Q

enterochromaffin cells

A

secrete serotonin

enteroendocrine cells of small intestine epithelium

24
Q

products of enteroendocrine cells in GI tract?

A
incretin
GIP
serotonin
somatostatin
motilin
cholecystokinin
neurotensin
VIP
substance P
endorphins

going to basal layer*** (not lumen)

25
somatostatin
stimulates homeostasis
26
paneth cells
secretions go out into lumen produce lysozymes and defensins -help degrade bacterial cell walls in the epithelium of small intestine in base of intestinal crypts -contain large acidophilic granules
27
M cell
in epithelium of small intestine -part of innate and classic immune systems capture and transport antigens to APCs and B cells in lamina propria likely located where there is a sharp fold in the villus border**
28
mucosa of small intestine
lamina propria - loose CT - prone to lymphoid infiltration - lots of plasma cells (in villus between crypts) secretory IgA lymphatic capillaries - lacteals
29
plasma cells
B lymphocytes | -antibody producing cells
30
histiocyte
macrophage in the gut lining
31
lacteals
lymphatic capillaries of the mucosa of small intestine
32
where do lymphatics originate?
blind ending channels in the villi of the intestine -aka lacteals not only place, but an important one pick up emulsified fat lacteals have no red blood cells**
33
peyers patches
in small intestine - lymphoid tissue that has become nodular in nature - like a lymph node in lamina propria of small intestine mucosa prominent in ileum may appear in lower jejunum
34
more M cells present where?
peyers patches
35
submucosa of small intestine?
projects into plicae circularies
36
auerbachs plexus
between layers of muscularis externa in intestine -inner circular/outer longitudinal PS ganglia - maintain muscle tone
37
myenteric plexus
on vascular channels | -dilation/constriction
38
serosa of duodenum
on anterior surface only -organ is retroperitoneal posterior is adventitia
39
ileocecal junction
site where ileum joins large intestine - formed by bolds of mucosa and submucosa - supported by mass of circular smooth muscle from muscularis externa
40
cecum
small, blind pouch of large intestine | -structurally indentical to colon
41
appendix
slender, blind diverticulum of cecum -small, irregular lumen often containing cellular debris villi are absent** intestinal crypts - enteroendocrine cells and some paneth cells
42
large intestine?
lack villi as means of surface amplication**
43
goblet cells in large intestine?
lots and lots because we are absorbing nutrients and water -so we have less and less hydrated material needs increased mucous production to help move along
44
paneth cells?
mainly in small intestine
45
crypts of lieberkuhn
intestinal crypts of large intestine | -larger and more closely packed than in small intestine
46
cells of large intestine?
crypts of lieberkuhn enteroendocrine cells paneth cells
47
epithelium of large intestine?
identical to small intestine - simple columnar epithelium - more numerous goblet cells virtually no digestive enzymes mainly water reabsorption
48
placa circulares
not present in large intestine
49
plica semilunares
present in the colon