Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 2 Renal > Interstitial and cystic kidney disease > Flashcards

Interstitial and cystic kidney disease Flashcards

1
Q

what is the most severe form of cystic renal dysplasia?

A

multicystic dysplastic kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the most dangerous complication from ADPKD?

A

subarachnoid aneurysm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

who gets screened for aneurysms?

A
  • family history

- normal renal function with PCKD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

tuberous sclerosis is a systemic disease characterized by multiple ____________

A

hamartomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is pathognomonic for tuberous sclerosis? what is the most common finding?

A
  • cortical brain tubers

- angiomyolipomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are the most common clinical manifestations of VHL?

A

retinal angiomas and cerebellar hemangiomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the manifestations of medullary cystic disease?

A
  • sodium wasting
  • anemia
  • renal insufficiency
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is used to diagnose medullary cystic disease?

A
  • excretory urography
  • sonography and CT scan
  • open renal biopsy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are the manifestations of medullary sponge kidney?

A
  • gross and microscopic hematuria
  • urinary tract infections
  • nephrolithiasis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the pathology in medullary sponge kidney?

A
  • defective urinary solute concentrating ability
  • inability to reduce urinary pH to 5.5
  • renal tubular acidosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the histology in medullary sponge kidney?

A
  • spherical, oval, or irregular enlargement of medullary and inner papillary portions of collecting tubules
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the 3 types of tubulointerstitial injury?

A
  • acute tubular necrosis
  • acute interstitial nephritis
  • chronic interstitial nephritis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the classic triad of acute interstitial nephritis?

A
  • low grade fever
  • skin rash
  • arthralgias
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the lab abnormalities in acute interstitial nephritis?

A
  • elevation in BUN and creatinine
  • abnormal UA
  • eosinophilia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the gold standard test for diagnosing acute interstitial nephritis?

A

biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are the pathological features of acute interstitial nephritis?

A
  • infiltration of inflammatory cells (lymphocytes, PMNs, eosinophils) in interstitium
  • edema
  • glomeruli and blood vessels are usually spared
17
Q

what drug classes can cause drug induced acute (and chronic) interstitial nephritis?**

A
  • abx
  • NSAIDs
  • diuretics
  • miscellaneous
18
Q

what is the presentation for chronic interstitial nephritis?

A
  • slowly progressing renal insufficiency
  • normal or sterile pyuria UA
  • mild proteinuria
  • HTN and anemia with moderate to advanced disease
19
Q

what are the pathological features of chronic interstitial nephritis?

A
  • atrophy of tubular cells with flattened epithelial cells and tubule dilation
  • interstitial fibrosis
  • cellular infiltration within the interstitial compartment and between tubules

Year 2 Renal (38 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions