Integumentary System Flashcards
What is the integumentary system?
the skin and the accessory structures
What does the integumentary system do?
protects, regulates temperature, senses things, begins the synthesis of Vitamin D
What are the three layers of skin?
epidermis, dermis, hypodermis (subcutaneous layer)
What are general traits of the epidermis?
made of stratified squamous epithelium; completely avascular (no blood vessels); thin areas can be 0.1 mm thick, thickest skin can be 1.5 mm; contains very few nerve endings;broken into five layers; 95% of the cells are keratinocytes
Five layers of epidermis
stratum corneum; stratum lucidum; stratum granulosum; stratum spinosum, stratum basale
What is stratum corneum?
dead, flat keratinocytes completely wrapped in keratin
What is stratum lucidum?
dead and flattened keratinocytes that give an extra layer
What is stratum granulosum?
keratinocytes expel liquids to form a barrier
What is stratum spinosum?
keratinocytes connect to one another with desmosomes; cells start to differentiate, and they cannot divide anymore
What is stratum basale?
keratinocyte-making stem cells and other cells are here; this is where the keratinocytes from the other layers were “born”, and they gradually pushed outwards; only found in thickest parts of skin
What are desmosomes?
specialized structures that use multiple different adhesion proteins to hold cells together and minimize the space between cells
What three cell types does stratum basale have?
Melanocytes, Merkel Cells, Langerhans cells
What are melanocytes?
produce black pigment called melanin. they produce more melanin in response to sunlight exposure. package small amounts of pigment in organelles called melanosomes. melanin absorbs UV rays from sunlight
What is skin color a factor of, and what is it NOT determined by?
it’s a factor of the number of melanosomes in the skin, and it’s not determined by the number of melanocytes
What does melanocytes generally have in their structure?
dendrites; the long projections reach into more superficial layers