Integumentary System 111 Flashcards
Healing occurs through
Regeneration: replaces injured tissue with the same kind of tissue
• Repair: fibrosis replaces injured tissue with scar tissue
Healing occurs through
Regeneration: replaces injured tissue with the same kind of tissue
• Repair: fibrosis replaces injured tissue with scar tissue
In skin, which tissue type undergoes regeneration, which undergoes fibrosis?
Epidermis-regeneration- cells undergo constant mitosis(labile cells) eg. Blood cells
Dermis- fibrosis- don’t have the ability to divide
Regeneration
Depends on the regenerative capacity of the cell
- the epidermis has stem cells that are constantly dividing so it can repair the layer above it
- need to know everything on diagram
True or False: scar tissue is as strong and flexible as healthy skin
False: Scar tissue can be weak as the healing process creates collagen bundles which don’t orientate themself for elasticity and flexibility
Fibrosis
In non-regenerating tissues and in severe wounds, fibrosis(scar) tissues replace the lost ones
The inflammatory phase
- the first phase
- there’s a lot of blood loss right away
- sometimes the bleeding is healthy to remove waste and toxins
- blood clotting stops the bleeding and prevents bacteria, toxins and other harmful substances from spreading
The proliferative phase
- epidermis regenerates(epidereliaization)
- dermis forms new blood vessels(angio(blood vessels)genesis) and fibroblasts lay down new collagen bundles(fibrogensis)
- young scars look pink due to blood vessels within the new tissue
The remodeling phase
The third phase
- overtime the fibroblast activities decrease and capillaries degenerate
- mature cells appears pink pale and contracts to pull wound margins together
First degree burns
First degree(superficial): epidermis only, redness, slight edema and pain
Eg. Most sunburns and flash exposure which is a short but rapid interaction with chemical or radiation to the skin
Second degree burns
- also known as partial thickness
- involves part of the dermis.
• skin discolouration and scars are common
E.g., scald or flash exposure , at a higher intensty
Third degree burns
- also known as full thickness
- involves all of dermis and possible deeper tissues
• white or charred in appearance
E.g., steam, hot oil, chemicals, electrical currents, flame, or infection
What is a characteristic of a second degree burn
Blisters- they are the separation of the epidermis and dermis
UV
Is a form of non-ionizing radiation
UV-A
- consists of 95% of the uv spectrum that enters the atmosphere
- has indirect dna damage through the production of reactive oxygen species(ROS), ex tanning