insuf cardiaca Flashcards

1
Q

ICC

A

-GC: insuficiente

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2
Q

hipertrofia

A

se presenta al inicio: disfuncion diastolica, el mecanismo se pierde y se dilata el corazon: disfuncion sistolica

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3
Q

remodelacion cardiaca

A

por sistema RAA, SN simpatico, dilatacion y adelgazamiento de paredes, fibrosis, colageno, rigidez

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4
Q

objetivo tx

A

1- aliviar sx
2- reducir, revertir detriorio miocardioco
3- prolongacion vida
4- mejor calidad de vida

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5
Q

farmacos

A

ionotropico positivo
diureticos de asa
IECA/ARA II
b- bloqueador
antiagregantes
diuretico ahorrador de K

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6
Q

ionotropicos +

A

digoxina
dobutamina, millrinona

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7
Q

Digoxina

A
  • sintomas, mejor vida
    inhibe: bomba Na/K: +Ca intracel
    activa SNPara: cronotropismo y dromotropismo negativo
    E: glucoprot P en cel TCP
    EA: anorexia, arritmias ventriculares, neurologicos
    intoxicacion: tx anti-digoxina
    antiacidos: - A, -excrecion: verapamilo, diltiazem
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8
Q

dobutamina

A

ag b-1: crono/ionotropico positivo, ag b.2: vasodilatacion
Tx ICC, choque cardiogenico

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9
Q

milrinona

A

inhibe fosfodiesterasa 3: +AMPc > +contractilidad
tx CC, choque cardiogenico

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10
Q

diuretico de asa: furosemida

A

en edema pulmonar
inhibe: NKCC2
vasodilatador. - vol > - edema > - precarga
EA: deshidratacion, hipo: natremia, potasemia, hiper: uricemia, glucemia

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11
Q

diureticos ahorradores de k

A

ant receptor de aldosterona, - mortalidad: ICG, - degradacion colageno, + remodelado vascular
EA: hiperpopotasemia
espironolactona, eplerenona

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12
Q

IECAS y ARAII

A

bloquean: angiotensina II, inhiben remodelado anormal miocardico
- incidencia ICC, -mortalidad, -velocidad progresion

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13
Q

b-bloqueadores

A

bloquea: actividad noradrenergica cardiaca, inhiben remodelado anormal miocardico, -RAA, + tolerancia ejercicio, +FEVI, - mortalidad, - hospitalizacion

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14
Q

farmacos b-bloqueadores

A

carvedilol: ant b1,2,a1, antioxidante
metoprolol
bisoprolol

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15
Q

tx no farmacologico

A

terapia de resincronizacion cardiaca, dispositivos de asistencia ventricular

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