antipsicoticos y antiepilepticos

Question 1

antipsicoticos tipicos

Answer 1

ant dopamina D2, ant H1: sedacion, ant a-1: hipotension
SI: S+, psicosis aguda, cronica, senil, +VD
NO: BZD, barbituricos, alcohol, litio
EA: extrapiramidales, hiperprolactinemia, amenirrea, galactorrea, ginecomastia, sd serotoninergico, sd neuroleptico maligno

Question 2

sd neuroleptico maligno

Answer 2

hiporreflexia
tx: dipenhidramina

Question 3

sd serotoninergico

Answer 3

hiperreflexia
tx: ciproheptadina

Question 4

farmacos tipicos

Answer 4

clorpromazina: - pot
haloperidol: + pot

Question 5

antipsicoticos atipicos, cara

Answer 5

ant fuerte SHT2A, debil D2, S-
SI: esqz resistente
EA: +lipidemia, +colesterol, +glucemia

Question 6

farmacos atipicos

Answer 6

clozapina: -VT, EA: agranulocitosis, neutropania, sd meatbolico
olanzapina: + usado
risperidona: +VT

Question 7

Antiepilepticos, clasif

Answer 7

retraso apertura canales Na
favorecer GABA

Question 8

retraso apertura canales de Na

Answer 8

carbamazepina
fenitoina
lamotriginas
topiramato

Question 9

carbamazepina

Answer 9

inhibe liberacion glutamato
tx neuralgia del 3, tonico-clonicas
induce su metabolismo
EA: tox hematologica grave: anemia aplasica, grnulocitosis

Question 10

difenilhidantoinato (fenitoina)

Answer 10

Tx tonico-clonicas
NO: ausencia
EA: nistagmo, ataxia, hirsutismo, hiperplasia gingival, sd Stevens Johnson

Question 11

lamotriginas

Answer 11

NO libera glutamato, modula canales de Ca

Question 12

topiramato

Answer 12

bloqueo R AMPA, KAINATO, (glut), + GABA
migraña, c parciales

Question 13

+ accion GABA

Answer 13

valporato
etosuximida

Question 14

valporato

Answer 14

-glutamato, modula Ca
interaccion: lamotrigina (AnE), lorazepam (BDZ)
EA: alopecia, hepatotoxico, pancreatitis

Question 15

etosuximida

Answer 15

modula Ca
SI: c. ausencia: 1eleccion
EA: extrapiramidales, fotofobia
2-3 trimestre: seguridad