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Periodontology > Inflammatory response > Flashcards

Inflammatory response Flashcards

1
Q

to fight an infection what do leukocytes travel through?

A

the blood stream

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2
Q

what is endothelium?

A

thin layer of epithelial cells that line the interior surface of blood vessels

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3
Q

what is transendothelial migration?

A

leukocytes pushing their way between endothelial cells to enter the connective tissue

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4
Q

what is chemotaxis?

A

leukocytes enter the connective tissue and are attracted to the site of infection due to chemicals released by bacteria

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5
Q

what is an example of a disease producing organism?

A

bacteria

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6
Q

inflammation facilitates ____ and _____

A

healing

repair

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7
Q

what is the inflammation response triggered by?

A

pathogens

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8
Q

there is an increased ____ to infected or injured tissue to deliver cellular defenders

A

blood flow

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9
Q

what leaks from capillaries into tissue at site of infection? also known as ___?

A

leukocytes and plasma proteins

-edema fluid

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10
Q

is it possible for the inflammatory response in the periodontium to destruct tissue cells, connective tissue, and bone?

A

yes

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11
Q

what are inflammatory biochemical mediators?

A

biologically active compounds secreted by cells that activate the body’s inflammatory response

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12
Q

3 mediators of importance in the periodontium

A
  1. cytokines
  2. prostaglandins
  3. matrix metalloproteinases
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13
Q

what are chemokines

A

a subgroup of cytokines that cause additional immune cells to be attracted to site of infection

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14
Q

What do the blood vessels initially do in the inflammation process

A

constrict

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15
Q

9 generalized steps of inflammation process

A
  1. BV constrict
  2. vessels dialate
  3. hyperemia-blood flow increases
  4. sludging
  5. margination
  6. pavementing
  7. emigration
  8. chemotaxis
  9. cells phagocytize bacteria
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16
Q

define sluding

A

vessels become more permeable resulting in decreased blood flow speed-clotting

17
Q

define margination

A

RBC move to center of blood vessels and WBC move to wall

18
Q

define pavementing

A

WBC adheres to wall of vessels

19
Q

define emigration

A

PMNs pass between endothelial cells into tissue

20
Q

what are the two stages of inflammation

A
  1. acute

2. chronic

21
Q

what is the acute inflammation process achieved by?

A

increased movement of plasma and leukocytes from the blood into the injured tissue

22
Q

what is an early sign of inflammation?

A

bleeding

23
Q

in the acute inflammatory response after the PMN’s arrive at the site, what do they release?

A

cytokines

24
Q

what do cytokines induce the liver to produce?

A

C-reactive protein

25
Q

if the acute inflammatory responses are not controlled, what does it become?

A

chronic

26
Q

T/F: chronic inflammatory response doesn’t cause more damage than the original problem

A

false; it does cause more damage

27
Q

if you don’t have a tooth you don’t have _____

A

bacteria

28
Q

are the 5 classic warning signs present in chronic inflammation?

A

no they are absent

29
Q

why does chronic inflammation occur?

A

the body is unable to rid itself of invading organisms

30
Q

the microorganisms are persistent and stimulate what kind of response in chronic inflammation

A

exaggerated host inflammatory response

31
Q

what kind of damage is done to the tissues with chronic inflammation?

A

permanent damage to the body tissues

32
Q

examples of chronic inflammation

A
  1. rheumatoid arthritis
  2. diabetes
  3. asthma
  4. gingivitis
  5. periodontitis
33
Q

S/S of chronic inflammation may partially/completely disappear during a period of _____ or may be in an active period of disease known as _____

A

remission

exacerbation

34
Q

____ destroy tissue and ____ destroys bone

A

MMP(Matrix metalloproteinases)

prostaglandins

35
Q

Chemical mediators that activate the body’s inflammatory response that are BAD:

A
  1. IL-1, IL-6, IL-8
  2. leukotrienes
  3. prostaglandins
  4. TNF-alpha

Periodontology (28 decks)

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