Inflammation And Tissue Repair

Question 1

Steps of inflammatory response

Answer 1

Recognition 
Recruitment 
Removal
Regulation 
Resolution and repair

Question 2

What are the mediators if inflammation

Answer 2

Microbes
Necrotic cells
Hypoxia

Question 3

Main characteristics of acute inflammatory

Answer 3

Edema

Neutrophil migration

Question 4

Examples of foreign bodies that cause inflammation

Answer 4

Urate crystals
Cholesterol crystals
Lipids

Question 5

High protein concentration and contains cellular debris

Answer 5

Exudate

Question 6

These leads to vascular congestion

Answer 6

Stasis

Concentration on red cells in small BV

Increased viscosity

Question 7

Causes the endothelium to contract

Answer 7

Histamine

Bradykinin

Leukotrinine

Question 8

Stimulates channels to promote transcytosis of fluids and proteins, promoting vascular leakage

Answer 8

VEGF

Question 9

They are easily disturbed by blood flow, promotes rolling of the leukocyte

Answer 9

Selectins

Question 10

Forms a firm adhesion for the leukocyte

Answer 10

Integrins

Question 11

Intracellular destruction of microbes and debris

Answer 11

ROS
Reactive Nitrogen
Lysosomal enzymes 
Antioxidants 
NET
Leukocyte mediated tissue injury

Question 12

Major vasoactive amine

Answer 12

Histamine

Serotonin

Question 13

Prostaglandin agent that is a Vasoconstrictor and platelet aggregate

Answer 13

Thromboxane A2

Question 14

Potent chemotactic agent and activator of neutrophil

Answer 14

LTB4

Question 15

Marked by the exudate on of poor cell fluid into spaces

Answer 15

Serous inflammation

Question 16

Due to increased vascular permeability

Answer 16

Fibrinous inflammation

Question 17

Pus build up

Answer 17

Purulent

Suppurative

Question 18

2 pathways of macrophages

Answer 18

Classical

Alternative

Question 19

Microbes and IFN gamma will lead to what pathway

Answer 19

Classical

Question 20

IL13 and IL 4 will lead to what pathway

Answer 20

Alternatively

Question 21

Activated macrophages that develop abundant cytoplasm and beyond to resemble epithelial cells

Answer 21

Epitheloid cell

Question 22

Fused multinucleated activated macrophages

Answer 22

Giant cells