Infectious Disease Flashcards
Examples of blood borne pathogens
Poliovirus
Hepatitis b virus
Trypanosomes
Examples of within the leukocytes
Herpesvirus
HIV
Mycobacteria
Spreads through red cells
Malaria
Enters the intestines but kills motor neurons
Poliovirus
An important mechanism for escape from antibody mediated host defenses
Antigenic variation
Theses has capability of resistance to antimicrobial peptide
Shigella
Staphylococcus aureus
Candida
This expresses protein A which binds to FC portion of the antibodies that inhibits phagocytosis
S aureus
Examples of injurious effects
Tuberculosis - type 4
HBV&HCV - immune response
Rheumatic Fever - cross reaction
Post strep GN- type 3
Factors for tissue tropism
Host cell receptor Cell lineage specific factor Anatomic barriers Local temp Ph Host defense
Mechanism of virus how they damage and kill cells
Direct cytopathic effects
Antiviral immune response
Transformation of infected cells
Characterized by increased vascular permeability and leukocytic infiltration and predominantly of neutrophils
Suppurative or purulent inflammation
Characterized by accumulation and aggregation of activated macrophages called epitheloid cells
Mononuclear and granulomatous inflammation
This is an exception to the host defense on skin
Larvae of schistosoma
Bacteria coordinately regulate gene expression within a large population process
Quorum sensing
Organisms live within a viscous layer of extracellular polysaccarchide that adhere to host tissue or devices
Biofilms