Infectious Disease Flashcards

1
Q

Examples of blood borne pathogens

A

Poliovirus
Hepatitis b virus
Trypanosomes

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2
Q

Examples of within the leukocytes

A

Herpesvirus
HIV
Mycobacteria

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3
Q

Spreads through red cells

A

Malaria

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4
Q

Enters the intestines but kills motor neurons

A

Poliovirus

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5
Q

An important mechanism for escape from antibody mediated host defenses

A

Antigenic variation

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6
Q

Theses has capability of resistance to antimicrobial peptide

A

Shigella
Staphylococcus aureus
Candida

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7
Q

This expresses protein A which binds to FC portion of the antibodies that inhibits phagocytosis

A

S aureus

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8
Q

Examples of injurious effects

A

Tuberculosis - type 4
HBV&HCV - immune response
Rheumatic Fever - cross reaction
Post strep GN- type 3

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9
Q

Factors for tissue tropism

A
Host cell receptor
Cell lineage specific factor
Anatomic barriers
Local temp
Ph
Host defense
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10
Q

Mechanism of virus how they damage and kill cells

A

Direct cytopathic effects
Antiviral immune response
Transformation of infected cells

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11
Q

Characterized by increased vascular permeability and leukocytic infiltration and predominantly of neutrophils

A

Suppurative or purulent inflammation

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12
Q

Characterized by accumulation and aggregation of activated macrophages called epitheloid cells

A

Mononuclear and granulomatous inflammation

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13
Q

This is an exception to the host defense on skin

A

Larvae of schistosoma

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14
Q

Bacteria coordinately regulate gene expression within a large population process

A

Quorum sensing

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15
Q

Organisms live within a viscous layer of extracellular polysaccarchide that adhere to host tissue or devices

A

Biofilms

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16
Q

What bacteria adheres to host tissue using adhesin protein f and teichoic avid to fibronectin

A

Streptococcus pyogenes

17
Q

Plays a role in septic shock, dic and adult respiratory distress syndrome

A

Endotoxins

18
Q

Causes it to adhere to junction protein and is expressed on epithelial cells

A

Nectin 4

19
Q

Pathognomonic of measels or rubeola

A

Koplik spot

Warthin finkeldey cells

20
Q

Where does poliovirus infect cells by binding to this epithelial adhesion molecule

A

CD 155

21
Q

Causes dengue fever and yellow fever

A

West nile virus

22
Q

HSV infected cells contain large, pink to purple intranuclear inclusions

A

Cowdry type A

23
Q

Causes chicken pox and shingles

A

Varicella zoster

24
Q

Shingles causing facial paralysis

A

Ramsay Hunt Syndrome

25
Q

Major determinant of whether a person clears the virus or becomes a chronic carrier

A

CTL

26
Q

Chronic hepatitis B virus can lead to

A

Cirrhosis of the liver and increased hepatocellular carcinoma

27
Q

What are seen in a PBS of px with EBV

A

Atypical lymphocyte

Downy cells

28
Q

A focal suppurative inflammation of the skin and subcutaneous tissue

A

Furuncle

Boil

29
Q

Example of category A

A

Anthrax

Botulism

30
Q

Category C bioterrorism

A

Nipah virus

Hanta virus