Immune 2

Question 1

2 characteristic manifestation of sjorgen syndrome

Answer 1

Keratoconjuctivitis sicca

Xerostomia

Question 2

Immunological mediated destruction of the glands can be due to

Answer 2

Autoimmune T cells

Immune reaction against viral infection

Question 3

This is expressed in 75% of the patient, which is an antibody against self IG

Answer 3

RF

Question 4

HLA DQA1 and HLA DQB1 has a specific allele to

Answer 4

SS-A

SS-B

Question 5

What syndrome is when your lacrimal and salivary glands are affected

Answer 5

Mikulicz syndrome

Question 6

What are the categories of systemic sclerosis

Answer 6

Diffuse scleroderma

Limited scleroderma

Question 7

Crest are seen in what type of scleroderma

Answer 7

Limited scleroderma

Question 8

This type of Ana are highly specific

Answer 8

Anas directed against DNA Topoisomerase 1

SCL-70

Question 9

This is found in 20-30% of px who tend to have CREST syndrome

Answer 9

Anticentromere antibody

Question 10

Two types of T cell mediated reaction

Answer 10

Acute cellular rejection

Chronic rejection

Question 11

What reaction is seen when direct killing of graft cells by CD8 and CTLs are a major component

Answer 11

Acute cellular rejection

Acute T cell mediated rejection

Question 12

3 types of antibody mediated reaction

Answer 12

Hyper acute

Acute

Chronic

Question 13

This is seen with pre formed antibodies

Answer 13

Hyperacute

Question 14

This reaction is seen after the transplant

Answer 14

Acute antibody mediated reaction

Question 15

This is a defect in phagolysosome and it is autosomal recessive e

Answer 15

Chediak higashi

Question 16

Defect in microbiocidal activity

X linked

Autosomal recessive

Answer 16

Chronic granulomatous Disease

Question 17

This defect in the TLR would result to herpes simplex encephalitis

Answer 17

TLR3

Question 18

This defect in TLR signaling are associated with destructive bacterial pneumoniae

Answer 18

Myd88