Implantation Flashcards
What are the chances of losing the embryo in the pre-implantation development?
20%-40%
What are the uterine cell types from center to extremity?
Endometrium, myometrium, perimetrium
Estradiol and progesterone promote uterine tissue _______________
Growth
Estradiol and progesterone are more present in which phase of ovulatory cycle?
Pre-ovulatory phase
Thinning of spinal arteries is due to ________ progesterone
Low
Which layer remains after shedding of uterine epithelium?
Basal layer of endometrium
What produces the progesterone required by the uterus?
The remains of the ovulated follicle (corpus luteum)
How does the embryo maintain the corpus luteum?
hCG binds to LH receptors on mural granulosa cells and theca cells and signals the development of corpus luteum
What is a diapause?
Embryo is fertilized and remains in the uterus before it is implanted
What factors are implicated in blastocyst-uterine attachment?
ErbB4, integrin, HB-EGF
What are the steps of implantation?
Apposition, attachment, invasion
Place the steps of invasion of the embryo into the uterine endometrium in order:
a) The SCT invades into the maternal deciduum
b) Cytotrophoblast cells derived from the trophectoderm push into SCT to generate chorionic villi
c) Cells of the trophectoderm fuse to generate the SCT
c, a, b
Where are the fetal blood vessels located?
Chorionic villi
Placental development brings maternal and fetal ____________ in proximity
Blood
Stem cells can be derived from which cell types?
Blastocysts, fibroblasts, muscle stem cells
