impetigo Flashcards
What is impetigo?
Impetigo is a common, superficial, highly contagious bacterial skin infection characterized by pustules and honey-colored crusted erosions.
Which layers of the skin does impetigo affect?
Impetigo affects the superficial layers of the epidermis.
What are the common pathogens that cause impetigo?
The common pathogens are Staphylococcus aureus and Streptococcus pyogenes (Group A beta-hemolytic streptococci).
What are the two types of impetigo?
Non-bullous (school sores) and bullous impetigo.
What is ecthyma?
Ecthyma is a deep form of impetigo that causes deeper erosions of the skin into the dermis.
What is impetiginisation?
Impetiginisation refers to the secondary infection of wounds or other skin lesions with the same pathogens that cause impetigo.
Who is most commonly affected by impetigo?
Impetigo is most common in young children but can occur at any age.
What skin conditions can predispose someone to impetigo?
Atopic dermatitis, contact dermatitis, scabies, and chickenpox.
What bacteria can cause non-bullous impetigo?
Non-bullous impetigo can be caused by Staphylococcus aureus, Streptococcus pyogenes, or both bacteria together.
How does non-bullous impetigo typically occur?
It occurs when a disruption in skin integrity allows bacteria to invade through the interrupted surface.
Which bacteria causes bullous impetigo, and what toxins does it produce?
Bullous impetigo is caused by Staphylococcus aureus, which produces exfoliative toxins (exfoliatins A and B).
What do exfoliative toxins target in bullous impetigo?
They target intracellular adhesion molecules (desmoglein-1) in the epidermal granular layer.
Where is non-bullous impetigo most commonly found?
Non-bullous impetigo is most commonly found on the face or extremities, but it can occur on any part of the body.
How does bullous impetigo present?
It presents as quickly appearing superficial, small or large thin-roofed bullae that tend to rupture and ooze yellow fluid, leaving a scaly rim (collarette).
How does non-bullous impetigo initially present?
It begins with a single erythematous macule that evolves into a pustule or vesicle.