Immunosuppresants Toxicity Flashcards

1
Q

Cyclosporine

A

NEPHROTOXICITY! HTN, HLD, Hyperglycemia, tremor, hirsutism, gingival hyperplasia.

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2
Q

Tacrolimus

A

Similar to cyclosporine, increased risk of diabetes and neurotoxicity; no gingival hyperplasia or hirsutism

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3
Q

Sirolimus (Rapamycin)

A

Anemia, thrombocytopenia, leukopenia, insulin resistance, HLD, NON-NEPHROTOXIC

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4
Q

Basiliximab

A

Edema, HTN, tremor

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5
Q

Azathioprine

A

Leukopenia, anemia, thrombocytopenia

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6
Q

Glucocorticoids

A

Hyperglycemia, osteoporosis, central obesity, muscle breakdown, psychosis, acne, HTN, cataracts, peptic ulcers

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