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Medicine > Immunology > Flashcards

Immunology Flashcards

1
Q

Define hypersensitivity

A

An excessive and inappropriate inflammatory response to any antigen

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2
Q

What mediates the early and late responses in allergy?

A

Early: mast cells and basophils
Late: eosinophils (after they have been mobilised from bone marrow)

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3
Q

Define atopy

A

Genetic predisposition to producing IgE in response to many, naturally-occurring allergens

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4
Q

What mediates Type I hypersensitivity

A

IgE

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5
Q

What mediates Type II hypersensitivity

A

Antibody

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6
Q

Examples of type II hypersensitivity reactions

A

ABO mismatch
haemolytic disease of newborn
Graves

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7
Q

What mediates Type III hypersensitivity

A

Antibody: but is soluble (forming immune complex)

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8
Q

Examples of type III hypersensitivity reactions

A

Farmer’s lung (mould spores)
Pigeon fancier’s disease
SLE
Post-strep GN

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9
Q

Examples of type IV hypersensitivity reactions

A

Contact dermatitis
T1DM
Hashimoto’s
RA

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Medicine (30 decks)

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