Immunology - 11

Question 1

How many polypeptide chains does an antibody have?

Answer 1

4:
2 identical heavy chains (HC)
2 identical light chains (LC)

Question 2

Do the light chains of an antibody touch each other?

Answer 2

No

Question 3

How are the polypeptide chains of an antibody held together?

Answer 3

• The two heavy chains are held together by disulfide bonds

* the light chains are bound to the heavy chains via a single interchange disulfide bond

Question 4

Which region of the antibody determines antigen specificity?

Answer 4

The variable region

Question 5

Which region of the antibody determines function?

Answer 5

The constant region

Question 6

Are the heavy chains within an antibody molecule identical or different?

Answer 6

Identical

Question 7

What provides different characteristics between the isotypes of antibodies (IgM, IgG, IgE, IgA)?

Answer 7

Different constant regions

Question 8

Are the light chains within an antibody molecule identical or different?

Answer 8

Identical

Question 9

Are the variable light chains the same or different for each antibody?

Answer 9

Different. Will be the same within an antibody but different between two different antibodies

Question 10

Are the constant light chains the same or different for each antibody?

Answer 10

Same

Question 11

How many amino acids does the variable region of the antibody comprise?

Answer 11

The first 110