Immunology - 06

Question 1

Where do you find the PRR and the PAMP?

Answer 1

PRR - on the macrophage

PAMP - it is the motif and it is on the pathogen

Question 2

Is macrophage phagocytosis a part of the innate or adaptive response?

Answer 2

Both.

Question 3

How is macrophage phagocytosis carried out in the innate response?

Answer 3

• PRR binding a PAMP

* opsonization (complement receptors binding pathogen covered in complement proteins)

Question 4

How is macrophage phagocytosis carried out in the adaptive response?

Answer 4

opsonization (Fc or complement receptors)

Question 5

What is it called when phagocytosis occurs after the binding of the antibody or complement?

Answer 5

Opsonization

Question 6

The antibody and the complement proteins are called what?

Answer 6

Opsonins

Question 7

Besides phagocytosis what is the role of the macrophage in both the innate and adaptive response?

Answer 7

Secrete cytokines to recruit more cells. In innate it also participates in inflammation

Question 8

Besides phagocytosis and secreting cytokines, what is another function of macrophages in the adaptive immune response?

Answer 8

Antigen presentation. Done through the MHC and presented to T cells