Immunology - 08 Flashcards
1
Q
What are the functions of the B cell?
A
- Recognize and bind antigen via the surface BCR
- antigen presentation
- after activation: production of antibodies (plasma cells), immunologic memory (memory B cells)
2
Q
Which isotypes are found on the surface of mature but naïve B cells?
A
IgM
IgD
3
Q
Which isotypes are found on the surface of mature, experienced B cells?
A
Only one isotype of: IgM IgG IgA IgE
4
Q
Which type of cells secrete antibodies?
A
Plasma cells (only one isotype of the atibody is secreted)
5
Q
Do T cells recognize whole pathogen/protein?
A
No, only peptides presented to their receptors by MHC
6
Q
Which are the two major subpopulations of T cells?
A
CD4+ (T helper cells TH, help other cells live up to their full potential by secreting cytokines)
CD8+ (cytotoxic T cells CTL)
7
Q
Which molecules do CD4+ and CD8+ recognize?
A
CD4+ regoconize = MHC class II CD8+ regoconize = MHC class I
Always equals 8 (4x2 or 8x1)
8
Q
Which are the antigen presenting cells (APC)?
A
- Dendritic cells
- macrophages
- B cells
