Immunology - 07

Question 1

What are the characteristics of neutrophils?

Answer 1

In both the innate and adaptive response:

• phagocyte
• most predominant granulocyte
• contains granules that have lytic enzymes secreted from the cell
• produce lots of cytokines
• often responsible for the immuno pathology associated with infection (collateral damage to host cells)

Question 2

What are the characteristics of eosinophils?

Answer 2

Bilobed nucleus

In the adaptive response:

• major role in parasitic infections
• involved in allergy/hypersensitivity

Question 3

What are the characteristics of basofils?

Answer 3

In the adaptive response:

* allergy and hypersensitivity

Question 4

What are the characteristics of mast cells?

Answer 4

• Granulocyte (granules contain histamine and other vasoactive molecules)
• high affinity IgE (adaptive) receptors
• major role in allergic reactions

Question 5

What are the characteristics of dendritic cells?

Answer 5

• Star-shaped morphology (cytoplasmic projections)
• rarely in circulation
• found predominantly in tissues (skin, lung, G.I., among others)
• phagocytes
• antigen presenting
• instead of recruiting cells to where they are fighting like macrophages, they act as messengers

Question 6

Where do the dendritic cells travel to when they pick up an antigen to present?

Answer 6

To the secondary lymphoid organs

Question 7

What are the characteristics of lymphoid cells?

Answer 7

• B, T, NK cells
• 20-40% of the body’s WBC’s
• 99% of the cells in lymph
• approximately 1 trillion lymphocytes in circulation (blood and lymph)
• can migrate into the tissue spaces and lymphoid organs

Question 8

What are the two main types of adaptive immune responses?

Answer 8

• Humoral (antibodies (B cells) )

* Cell-mediated (T cells)