Immunology - 04

Question 1

Where do T cells and B cells mature?

Answer 1

B cells - in bone marrow

T cells - in thymus

Question 2

Where in the periphery are T cells found?

Answer 2

lymph nodes and spleen

Question 3

Where in the periphery are B cells found?

Answer 3

lymph nodes, spleen, Peyer’s patches, tonsils

Question 4

What is the difference in the lifespan of neutrophils and macrophages?

Answer 4

Neutrophils are short lived (found in blood, travel to tissue)
Macrophages are long lived (patrol the tissue)

Question 5

What are Pattern Recognition Receptors (PRR)?

Answer 5

Recognize common motifs/patterns present on pathogens (Pathogen-Associated Molecular Patterns (PAMPs))

Question 6

Which are the PRR’s?

Answer 6

• Toll-like receptors (TLR) which recognize and bind PAMPs to cause activation of the cell
• other types not discussed

Question 7

Which immune cells migrate from blood to tissue?

Answer 7

Neutrophils and monocytes

Question 8

What enhances the expression of adhesion molecules on the surface of endothelial cells?

Answer 8

Cytokines released during the immune response

Question 9

What is the term for when cells pass-through capillaries into tissues called?

Answer 9

Extravasation

Question 10

Which type of cells release enzymes in granules to kill bad guys?

Answer 10

Neutrophils