Immunology - 03

Question 1

Which immunity recognizes motifs rather than specific antigen?

Answer 1

Innate

Question 2

Which are the arms of the innate immune response?

Answer 2

• Barrier defense (physical and physiological)
• Soluble defense (complement)
• Cellular defense (Phagocytosis and release of cytokines)
• Inflammation

Question 3

Which are the physiologic barriers of the innate response?

Answer 3

• Fever (retards growth, speeds hematopoiesis)

* pH (kill pathogens, retards growth)

Question 4

Does complement function in innate or adaptive response?

Answer 4

Both.

Question 5

How does complement get activated in innate response?

Answer 5

Recognition of bacterial surface elements (LPS) or mannose-binding lectin (MBL) protein binding mannose on bacterial surfaces

Question 6

Which cells are polymorphonuclear cells (PMNs) due to a segmented nuclei?

Answer 6

Neutrophils

Question 7

Which cells have granules that contain enzymes (defensins)?

Answer 7

Neutrophils

Question 8

What do neutrophils do at a combat site?

Answer 8

Phagocytic and cytotoxic

Question 9

Which cells differentiate when it enters the tissues and becomes “tissue fixed”?

Answer 9

Monocytes - become macrophage