Immuno 2 Flashcards
1
Q
What HLAs are assoc w/ MHC I?
A
HLA-A, HLA-B, HLA-C
2
Q
What HLAs are assoc w/ MHC II?
A
HLA-DR, HLA-DQ, HLA-DP (“Dr. Dairy Queen, Dr. Pepper”)
3
Q
HLA-A3 is assoc w/ wha?
A
Hemochromatosis
4
Q
HLA B27 is assoc w/ what?
A
“PAIR” Psoriatic arthritis, Ankylosing spondylitis, Inflammatory Bowle Disorder, Reiter Syndrome
5
Q
What is HLA-DR3 and HLA-DR4 assoc w?
A
DM Type I
6
Q
What molecules are expressed on APC dendritic cells?
A
MHC II, MHC I, B7 co-stimulatory signals (CD80 and CD86), and CD40
7
Q
What are the 3 main APC?
A
B cells, dendritic cells, macrophages
8
Q
What is the characteristic EM look like for Langerhan histiocytosis?
A
Birbeck granules (look like tennis rackets)
9
Q
What markers do Langerhans cells express?
A
S-100 and CD1a
10
Q
What type of cell are Langerhans cells?
A
Dendritic cell
