Immune System Flashcards
antigens
foreign substances
-identification to detect agents that are dangerous and let them know their foreign
allergies
immune response to foreign agents that are NOT pathogens
innate immune system
- external aspect of innate immune system (first line of defense)
- doesnt defend against specific pathogens
- HAS NATURAL KILLER CELLS
normal flora
live on skin/ other substances lining areas in contact with external environment
immune system
- 2nd line of defense
- collection of nonspecific cellular response such as…
- inflammation
- production of interferons
- ingestion of pathogens by phagocytes
adaptive immune system
- 3rd line of defense
- collection of cellular responses triggered by internal presence of SPECIFIC antigens
T- Cells
- undergo mutation in THYMUS
- in presence of antigen, mature T-cells activate - DIRECTLY attack cells infected by viruses and bacteria(Helper, cytotoxic, and memory)
Helper T-Cell
- secretes INTERLEUKINS, chemical messengers that trigger action of other cells
- one of those action is attack of foreign
substances by cytotoxic T-cell
-activate B cells to make ANTIBODIES and other chemicals
Memory Cell
- T cell that now responds quickly to an antigen re-exposure
- involved in cell mediated immunity
B-cell
- make antibodies in response to antigens
- multiply quickly into plasma cells (produce and secretes large amount of antibodies)
- production of immunoglobin
antibody
- blood proteins that have variable region that fits specific antigens
- tags pathogens for later destruction
passive immunity
- temporary immunity gained by body
- gained NATURALLY
active immunity
- protection against specific antigens resulting from body’s production of antibodies in response
vaccine
- solution of dead and weakened pathogens introduced to body for purpose of stimulating antibodies production
Peyer’s patch
protects digestive system from pathogen
macrophage
one large type of phagocyte WBC
-after consuming pathogen, theyre able to put parts of ingested antigens on cell membrane to alert patrolling T-cells
cytokines
broadcast location of pathogens to other WBC
Spleen
- Filters blood
- removing microbes and worn out rbc
- produces white blood cells that fight infection and synthesizes antibodies