Immune System Flashcards

1
Q

The immune system is primarily responsible for acting as a line of ______ against _____ that enter the body.

A

line of defense; pathogens

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2
Q

_______ are any foreign substances that cause disease or infection.

A

Pathogens

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3
Q

Pathogens include:

A

viruses
bacteria
fungi

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4
Q

The immune system is split into what two systems?

A

Innate and adaptive

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5
Q

How does the innate system prevent disease vs the adaptive system?

A

The innate system uses nonspecific defenses to prevent disease; the adaptive system targets specific pathogens.

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6
Q

What is the bodies first line of defense against microorganisms that can cause harm?

A

the skin acts as a barrier

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7
Q

What traps pathogens that enter the mouth, eyes, or nose?

A

cilia; tears; mucus; saliva

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8
Q

What does the innate immune system initiate as a response to pathogens that have entered the body?

A

inflammation

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9
Q

If a body tissue is damaged, the local tissue releases what to raise the temperature of the body and increase blood flow to that area?

A

histamines

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10
Q

When your body increases blood flow to an area of injury, you are increasing the amount of _______ flowing that site for tissue repair.

A

neutrophils

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11
Q

When enough pathogens enter the body, the body will trigger the release of enough histamines to raise the overall body temp, resulting in a _______, which is another innate immune response.

A

fever

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12
Q

Innate Response - _________ ______ destroy bacteria by interfering with the functions of their membranes and DNA

A

Antimicrobial Peptides

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13
Q

________ causes nearby cells to increase their defenses and can possibly inhibit virus replication.

A

interferon

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14
Q

The adaptive immune system ________ targets pathogens and attacks them based on their specific ______.

A

specific; properties

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15
Q

What is a substance that exists on the surface of a pathogenic cell that the immune system does not recognize?

A

antigens

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16
Q

The main actors of the adaptive immune system (specific) are the _______.

A

lymphocytes

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17
Q

Two types of lymphocytes:

A

B and T lymphocytes

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18
Q

B - lymphocytes are produced in the _____ _____.

A

bone marrow

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19
Q

T - lymphocytes mature in the ______.

A

thymus

20
Q

The B - lymphocytes participate in the ______ response.

A

humoral response

21
Q

T - lymphocytes participate in the ____ - _____ response.

A

cell mediated

22
Q

The humoral respons e of the B - lymphocytes comes into play when the virus is basically floating around _____ of the cells.

A

outside

23
Q

When the virus infiltrate the cells, the ___ lymphocytes are activated.

A

T

24
Q

White blood cells are called ________.

A

leukocytes

25
Q

What are the two classes of white blood cells?

A

granular and agranular leukocytes

26
Q

What are the granular leukocytes?

A

neutrophils
eosinophils
basophils

27
Q

What classes are the agranular leukocytes divided into?

A

lymphocytes

monocytes

28
Q

What is the first lymphocyte to detect an antigen?

A

T - Cell

29
Q

When a phagocyte ingests a pathogen cell, T-cells are alerted to the presence of _______ that now exist in the phagocyte membrane.

A

antigens

30
Q

What type of T-Cell is activated in an immune response, and acts as the coordinator of the immune response?

A

Helper T - Cells

31
Q

Why are helper T - Cells called the coordinators of the immune response?

A

they can stimulate one of two different kinds of immune responses

32
Q

What two responses can a helper T-Cell stimulate in an immune response?

A

The cytotoxic T-Cells and the B-Cells

33
Q

The cytotoxic T-Cells act in a ____ - ______ response.

A

cell - mediated response

34
Q

The cytotoxic cells ____ to the _______ cell’s surface in order to kill it.

A

bind; targeted

35
Q

When B cells are triggered, an ______ - ________ response is triggered.

A

antibody - mediated response

36
Q

Antibodies are _______ that bind to the antigen to _______ it and stimulate phagocytes to ingest the entire structure.

A

bind; neutralize

37
Q

What are the two types of B cells that arise in an antibody mediated response?

A

plasma cells; memory cells

38
Q

What produces antibodies?

A

plasma cells

39
Q

What stores the info from the antibodies, then are quickly sprung into action if the same antigen appears in the body?

A

memory cells

40
Q

The resistance to a now-known pathogen is called ______.

A

immunity

41
Q

Memory B - cells are the underlying mechanisms behind _______.

A

vaccines

42
Q

Neutrophils, a granulocyte are the ______ ______ and quickly migrate to the site of _______ to destroy bacterial invaders.

A

first responders; infections

43
Q

Eosinophils, a granulocyte, attack _______ _______.

A

multicellular parasites

44
Q

Basophils, a granulocyte, is a large cell responsible for _________ ______, including ______.

A

inflammatory reactions; allergies

45
Q

What type of monocyte engulfs and destroys microbes, foreign substances, and cancer cells?

A

macrophage

46
Q
Name whether the following are innate or adaptive immunity.
Neutrophil
Eosinophil
Basophil
B-Cells
T-Cells
Natural Killer Cells
Marophage
A
Neutrophil - innate
Eosinophil - innate
Basophil - innate
B - Cells - adaptive
T - Cells - adaptive
Natural Killer Cells - both
Marcophage - both
47
Q

Natural Killer Cells destroy ____ - _____ cells and _____ cells.

A

virus - infected cells; tumor