Immune System Flashcards

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1
Q

These are produced by B cells and are designed to track down and bind to pathogens

A

Antibodies

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2
Q

This region of the antibody is the same across all antibodies of the same type

A

Constant region

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3
Q

These variables differ in order to detect a diverse range of foreign molecules- antigens

A

Hypervariable and variable region

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4
Q

Which region of the antibodies so contain the antigen binding site

A

Hypervariable region

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5
Q

This causes antibody’s 1 to 1 specificity

A

Antibody binding site

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6
Q

Site where antigens is recognized by an antibody

A

Epitope

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7
Q

Where are white cells produced

A

Bone marrow

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8
Q

Difference between RBCs and WBCs

A

WBCs are nucleated

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9
Q

This accounts for 60% of leukocytes and they track down foreign pathogens, like bacteria by consuming and destroying through phagocytosis

A

Neutrophils

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10
Q

This accounts for 30% of leukocytes. This consists of T cells, B cells, and Natural Killer cells

A

Lymphocytes

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11
Q

These target and destroy infected host cells

A

Natural Killer (NK) cells

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12
Q

These make up 5% of WBC. They are the largest leukocyte by size and can differentiate into 2 further cell types: macrophages and dendritic cells

A

Monocytes

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13
Q

These are phagocytes that dispose oft cellular debris and non-cellular foreign material

A

Macrophages- like the clean up crew

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14
Q

These WBCs target parasitic infections

A

Eosinophils

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15
Q

These WBCS are inflammatory cells that release histamine as part of allergic response

A

Basophils and Mast cells

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16
Q

Neutrophils, eosinophils, and basophils are immune cells that contain cytoplasmic granules rich in proteolytic enxymes

A

Granulocytes
Eosinophils: red
Basophils: blue

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17
Q

Production of red and white blood cells in bone marrow

A

Hematopoiesis

18
Q

This section of the spleen is rich in lymphocytes and are important sites of B cell activation

A

White pulp of spleen

19
Q

This is where T cells mature

A

Thymus

20
Q

System of vessels that help transport fluid and immune cells throughout the body

A

Lymphatic system

21
Q

Colorless, lipid-rich fluid that flows through the lymphatic system

A

Lymph

22
Q

Pockets for lymphatic tissue that house high concentrations of T and B cells

A

Lymph nodes

23
Q

4 main functions for the lymphatic system

A
  1. Maintains fluid balance
  2. Collecting and returning interstitial fluid to circulation
  3. Transporting cells and biomolecules within lymph
  4. Producing lymphocytes
24
Q

Any action of the immune system directed towards healthy host tissues

A

Autoimmunity

25
Q

This enzyme breaks down bacterial cell walls in the mouth

A

Lysozyme

26
Q

Symptoms of inflammation

A

Calor- heat
Dolor- pain
Rumor-redness
Tumor- swelling

27
Q

T or F. Inflammation causes vasodilation which increase blood flow in the area

A

True

28
Q

Innate vs Adaptive Immune System

A

Innate:
1. Non-specific and responds to injury and infection
Adaptive:seeks special targets and remembers pathogens

29
Q

2 primary cell components of Adaptive Immune system

A

B cells and T cells

30
Q

T cells that fail to respond to putative antigens are eliminated by?

A

Positive selection

31
Q

T cells that are too reactive are eliminated by?

A

Negative selection- selects for T cells that would not provoke an autoimmune response

32
Q

This T cells responses to MHC1

A

T-cell CDB receptor

33
Q

Non self antigen displayed in MHC1 is recognized by what

A

CD8 Surface proteins of cytotoxic T cells (killer T cells)

34
Q

Difference between MHC I and MHC II receptors

A

MHC I- found in all cells

MHC II- found on certain immune cells like macrophages and dendritic cells

35
Q

These cells recognize MHC II receptors of antigen-presenting cells

A

Helper (CD4) T cells

36
Q

What does the helper T cells do when it see an antigen-presenting cell displaying an antigen

A

Secrets a series of cytokines- activate other immune cells increasing the strength of the immune response

37
Q

Which T cells can be memory T cells

A

Killer T cells and Helper T cells

38
Q

Which cells is responsible for the humoral response

A

B cells

39
Q

If a B cell encounters an antigen that it has a matching receptor for what are the 2 things that it can do?

A
  1. Mature into short-lived plasma cell- produce antibodies

2. Turn in to memory B cell

40
Q

T or F. The humoral response is part of the cell-mediated response.

A

False. It is not part of the cell0mediated response

41
Q

Humoral vs Cell-mediated

A

Humoral- B cells

Cell-mediated- T cells