Imaging in inflammatory disorders

Question 1

Molecular imaging

Answer 1

radionuclide imaging

Question 2

Properties of an ideal isotope

Answer 2

half-life similar to the length of examination

gamma emitter

available at hospital site

easily bound to pharmaceutical agent

radiopharmaceutical should be eliminated in similar half-time to duration of examination

Question 3

Gamma radiation

Answer 3

gamma rays occur due to the radioactive decay of unstable isotopes

Question 4

Single photon emission computed tomography (SPECT)

Answer 4

CT version of nuclear medicine

gamma cameras rotate around the area of interest

Question 5

Positron Emission Tomography (PET)

Answer 5

Molecular imaging

image biologically interesting processes

uses radionuclides that decay b positron emission

proton –> neutron + positron

Question 6

Radiation Risks

Answer 6

Ionising radiation is the main risk

risk of inducing fatal cancer

Question 7

Benefits of radiation

Answer 7

diagnosis, management change, treatment