hypertension drugs Flashcards

1
Q

how can you lower CO?

A

decrease HR/contractility
lower circulating volume

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2
Q

how can you lower total peripheral resistance?

A

decrease vascular tone eg vasodilator

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3
Q

what are B1 receptors and what do they do?
what is the effect of blocking them?

A
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4
Q

what are B2 receptors and what do they do?
what is the effect of blocking them?

A
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5
Q

what are B1 selective blockers?
examples, when used?

A
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6
Q

what are B1B2 nonselective blockers?
examples, when used?

A
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7
Q

what are B1B2A1 blockers?
examples, when used?

A
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8
Q

what are partial agonist B blockers?

A
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9
Q

what are s/e of B blockers?

A
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10
Q

why do you have to be cautious using B blockers in diabetes?

A
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11
Q

why do you have to be cautious using B blockers in asthma/copd?

A
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12
Q

why do you have to be cautious using B blockers in decompensated HF?

A
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13
Q

what are the overdose effects of B blockers?

A
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14
Q

how do you treat B blocker overdose?

A
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15
Q

what are A1 blockers?
examples, when used, s/e?

A
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16
Q

what is Clonidine - A2 blockers?
s/e?

A
17
Q

what are A2 receptors?

A
18
Q

examples of A2 blockers?

A

clonidine
methyldopa

19
Q

what is methylopda - A2 blockers?
s/e?

A
20
Q

what are CCBs?

A
21
Q

what ae the effects of each CCB class?

A
22
Q

how does each CCB class work?

A
23
Q

what are dihydropyridines?
use, example, s/e

A
24
Q

what are non-dihydropyridines?
use, example, s/e

A

constipation, commonly with verapamil
rise in prolactin - hypogonadism, decreased libido, impotence, irregular meses, galactorrhoea
gingival hyperplasia

25
Q

which drugs act on angiotensin 2?
s/e?
examples?

A
26
Q

what are se in ACEi?

A
27
Q

what is aliskiren?

A
28
Q

what are examples of diuretics?

A
29
Q

what is hydralazine?

A
30
Q

what is drug-induced lupus?

A
31
Q

what drugs are used in hypertensive emergency?

A
32
Q

what are the aims of drug tx in hypertensive emergency?

A
33
Q

what is orthostatic hypotension?
causes, features

A
34
Q

what drugs can cause orthostatic hypotension?

A
35
Q

what is reflex tachycardia?
causes?

A
36
Q

how to choose drugs best for patient based on diabetes + systolic HF?

A
37
Q

how to choose drugs best for patient based on pregnancy + renal failure?

A