cardiac action potentials Flashcards

1
Q

what is the cardiac action potential?

A
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2
Q

when one cell depolarises, what helps transmit the depolarisation to other cells?

A

gap junctions

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3
Q

what is phase 4 of action potential?

A
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4
Q

what is phase 0 of action potential?
which class of anti arrhythmic drugs acts on phase 1 and what do they do?

A
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5
Q

what is phase 1 of action potential?

A
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6
Q

what is phase 2 of action potential?
which class of anti arrhythmic drugs acts on phase 2 and what do they do?

A
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7
Q

what is phase 3 of action potential?
which class of anti arrhythmic drugs acts on phase 3 and what do they do?

A
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8
Q

how does myocyte vary to skeletal muscle action potential?

A
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9
Q

what is the refractory period?

A
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10
Q

where can myocyte action potential be found?

A

Bundle of HIS, bundle branches, purkinje fibres, atrial + ventricular myocytes

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11
Q

what action potential is found in the SA and AV nodes?

A

pacemaker action potential

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12
Q

describe the pacemaker action potential

A
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13
Q

what is automaticity and no fast Na+ channel activity in pacemaker cells?

A
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14
Q

what are the effects of drugs that act on pacemaker cells in Sa and AV nodes?

A
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15
Q

what are the drugs that block pacemaker potential?

A
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16
Q

how do verapamil/diltiazem work?

A

SLOW PHASE 0

17
Q

how do B blockers work?

A

prolong repolarisation, slow AV node conduction

18
Q

what modifies HR by modifying slope of phase 4?

A
19
Q

what are the pacemakers in the heart?

A