Hypercalcaemia Flashcards

1
Q

What can cause hypercalcaemia in malginancy?

A

Production of PTHrP

  • increases vit D3
  • increases bone resorption
  • increases renal reabsorption

Bone invasion

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2
Q

What are features of hypercalcaemia?

A
Nausea
Increased thirst
Constipation 
Abdominal pain
Confusion
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3
Q

How is hypercalcaemia managed?

A

Rehydration for at least 24 hours

Bisphosphonates

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4
Q

When should you be cautious with bisphosphonates?

A

Poor renal function

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