Head & Neck Tumours Flashcards
Where do H&N tumours often arise?
Mucosa
What are risk factors for H&N tumours?
Lifestyle
- smoking
- alcohol
- betel nut
Viruses
- HPV 16 + 18
- EBV
Occupational
- wood dust
- asbestos
- formaldehyde
What are symptoms of H&N tumours?
Depend on location
Lymphadenopathy
What symptoms can advanced tumours cause?
Breathing problems
Eating problems
Carotid involvement
Hoarse voice
What are signs of H&N tumours?
Lymphadenopathy Hoarse voice Prolonged oral ulcer Leukoplakia Erythroplakia
What investigations are done for suspected H&N tumours?
Ultrasound + FNA FNE (fibreoptic nasoendoscopy) CT / MRI Panendoscopy PET P16
What is P16?
Staining using immunohistochemistry
How are H&N tumours managed?
MDT
Radical
- surgery
- chemoradiotherapy
Palliative
- chemo
- radiotherapy
Who is involved in an MDT for H&N tumours?
ENT
Maxillofacial
Dietician
SALT
What sites can H&N tumours affect?
Lip/oral cavity
Pharynx
- oropharynx
- nasopharynx
- hypopharynx
Larynx
- supraglottis
- glottis
- subglottis
Nasal cavity
Salivary glands
Thyroid
How are H&N tumours staged?
TMN staging
How do oral cavity tumours present?
Lump Pain Tongue fixation Dysphagia Odynophagia
How are oral cavity tumours investigated?
Biopsy
CT/MRI
How are oral cavity tumours managed?
Surgery
Radiotherapy
How do pharyngeal tumours present?
Lump
Pain
Dysphagia
Weight loss