Hyperaldosteronism

Question 1

Hyperaldosteronism

Answer 1

Endocrine disorder where adrenal gland produces above normal levels of aldosterone

Question 2

Aldosteropn phys

Answer 2

1. Aldosterone is made by the adrenal medulla most inner layer called zona glomerulosa
2. Released in response to renin and bind to distal convulated tubule of the nephron
3. Stimulate Na/K pump to work harder so more Na+ enters the blood and so water follows
4. This increases blood volume and blood pressure

Question 3

Function os Aldoesterone ( angiotensin and renin too)

Answer 3

1. Decrease potassium levels
2. Increase sodium levels
3. Increase blood volume and blood pressure

Question 4

Causes of hyperaldosterone
( PRIMARY CAUSES)
( low renin/ high aldosterone)

Answer 4

1. Idiopathic hyperaldosteronism - zoma glomerulosa has an increase in aldosterone secreting cells
2. Conn syndrome - tumor secretes too much aldosterone
3. Familial Hyperaldosteronism - genetic, zona glomerular cells make aldosterone inappro

Question 5

Secondary causes of hyperaldosteronism

high aldosterone/ high level of renin

Answer 5

1. Chronic increase in blood pressure ( CHF/Cirrhosis) –Excess aldosterone production as a result of excess renin levels

Question 6

Clincial feat of hyperaldosteronism

Answer 6

1. Hypokalemia
2. Hypernatremia - high Na in the blood means more water so higher bp
3. Hypertension
4. Metabolic alkalosis- loss of proton in blood

Question 7

Symtpoms of hyperaldosteronism

Answer 7

Hypokalemia - constipation, weakness, heart arrythmia

Hypertension - headaches and flushing