Hyper 3

Question 1

Hypersensitivity Type III deals mainly w/ what type of complexes?

Answer 1

immune complexes that have precipitated out and deposit into tissues (not broken down)

Question 2

three circumstances that cause immune complex deposition?

Answer 2

1) persistent low grade infection
2) autoimmunity
3) direct formation of immune complexes on body surfaces (lung)

Question 3

four factors determining immune complex deposition

Answer 3

• size - intermediate - most deposition
• clearance - faster = less likely
• antigenic change - (+) charge likely to deposit in kidney
• anatomic/hemodynamic factors - i.e. vasculitis

Question 4

what is vasculitis? Four common places it can take place:

Answer 4

slamming against tortuous course causing antigen deposition

-glomerulous, ciliary body, choroid plexus, arteries

Question 5

vasculitis: deposition in ____
nephritis: deposition in the _ _
arthritis: deposition in __ __

Answer 5

arterioles
renal glomerulous
joint synovia