Hydrocephalus and Lumbar Puncture Flashcards
what is hydrocephalus?
a conditions where there is excess cerebrospinal fluid within the intracranial space and the intra-ventricular spaces.
where is the majority of CSF produced?
the choroid plexus:
> temporal horn roofs and body floors of lateral ventricles
> posterior 3rd ventricle roof
> caudal 4th ventricle roof
describe the CSF production process
it is metabolically active, sodium is pumped into the subarachnoid pace and water follows from the blood vessels
describe the CSF pathway
> from the 2 lateral ventricles
through the foramen of monro into the 3rd ventricle
through the cerebral aqueduct into the 4th ventricle
through either the foramen luschka (paired) or foramen magendie (midline)
subarachnoid space around the brain and spinal cord
reabsorption into venous sinuses
how is CSF reabsorbed back into the venous system?
through numerous arachnoid granulations along the Dural venous sinuses which contain arachnoid villi.
how do arachnoid villi function?
they are a pressure dependent one way valves that open when the intracranial pressure is 3 to 5cm h2o greater than dural venous sinus pressure
what drives CSF reabsorption?
the pressure gradient between the intracranial space and the venous system
name the two major distinctions of hydrocephalus
> communicating hydrocephalus
> non-communicating hydrocephalus
describe communicating hydrocephalus
the CSF can travel from the choroid plexus to the arachnoid granulations
what happens if CSF production is larger than CSF resorption?
there is communicating hydrocephalus
what is the result of communicating hydrocephalus?
> ventricular system dilates uniformly
> intracranial pressure rises
what rare condition could lead to overproduction of CSF?
choroid plexus papillomas
how can communicating hydrocephalus present in children whose cranial sutures have not fused?
> disproportionate increase in head circumference compared to the rest of the face, prominent frontal bossing
venous scalp distension
failure to thrive
what signs and symptoms can be seen in communicating hydrocephalus in a patient with fused sutures?
> papilledema
gait disturbance
6th cranial nerve palsy
upgaze difficulty
what is the aetiology of communicating hydrocephalus?
> infection (bacterial meningitis)
subarachnoid haemorrhage
post operative
head trauma
when can neurological decline due to communicating hydrocephalus be rapid?
if a significant number of arachnoid granulations are impaired there will be a rapid decline in CSF reabsorption due to high turnover is a normal individual
when does non-communicating hydrocephalus occur?
whenever there is any physical obstruction to the normal flow of CSF before it leaves the ventricles
what can cause non-communicating hydrocephalus?
> aqueductal stenosis > tumours > cysts > infection > haemorrhage/haematoma > congenital malformations/conditions
what is the earliest radiographical indicative finding of the development of hydrocephalus?
dilation of the temporal horns of the lateral ventricles (in most young and middle aged patients these should normally be invisible)
what is the treatment for acute hydrocephalus?
surgical: external ventricular drain. if this cannot be maintained indefinitely then a permanent shunt will be required.
what different types of shut replacement is available for communicating hydrocephalus treatment?
> ventriculo-peritoneal
lumbar peritoneal
ventriculo-atrial (in peritoneal failure)
what is the treatment for non-communicating hydrocephalus?
> surgical removal of the obstructing lesion can sometimes avoid shunt
third ventriculostomy