Humoral Immune 1- Part 5

Question 1

Short lived plasma cells survive up to _ wks, and live in spleen and lymph nodes after immunization

Answer 1

2

Question 2

Long lived plasma cells live months - ______, accumulate in bone marrow

Answer 2

Years

Question 3

Long-lived resting memory cells:
Survival does ____ depend on antigen contact

Answer 3

NOT

Question 4

Large and dividing memory cells:
Survival ________ on antigen contact

Answer 4

Depends

Question 5

Memory cells survival in humans =

Answer 5

60 years

Question 6

B cells in the germinal center undergo SOMATIC mutation as they respond to antigen presented by _________ cells

Answer 6

Dendritic

Question 7

If the mutation enables them to bind more strongly, they will be stimulated to _____ further

Answer 7

Grow

Question 8

If the mutation reduces their antigen-binding ability, the B cells will undergo __________

Answer 8

Apoptosis

Question 9

What Ig antibody is in the highest concentration in serum?

Answer 9

IgG

Question 10

What Ig is very high in serum with 5 subunits?

Answer 10

M

Question 11

How many subunits do IgA have in serum?

Answer 11

2

Question 12

Where are the IgA and IgE antibodies produced?

Answer 12

Intestinal and respiratory tracts

Question 13

Where are IgM, G, and D produced?

Answer 13

Spleen and lymph nodes

Question 14

Ig_ is very important for inflammation
Activates the classical complement pathway

Answer 14

G

Question 15

Ig_ is in serum and pentagram structure
Has a joining protein
Not very important for inflammation

Answer 15

M

Question 16

Acting as a BCR, Ig_ is an Ig monomer

Answer 16

M