Cellular Immune 1- Part 1 Flashcards
What type of cells regulate immune response?
Helper T cells (Th)
What type of cells destroy cells expressing endogenous antigens?
Cytotoxic T cells (Tc)
What type of cells control everything?
Regulatory T cells
What cells are responsible for antibody production?
B cells
What are the function of the following receptors:
TCR, MHC class 1, MHC class 2, BCR?
Antigen binding
What are made of immunoglobulin proteins or domains?
Antigen binding receptors
All ______ are membranes of the immunoglobulin superfamily
Proteins
What is the order from outside to inside of the cell of proteins binding antigens?
Outside - variable domain
Middle- constant domain
Inside- trans membrane domain
_ cells are divided into subpopulations based on antigen receptors, on the ________ molecules and on their function
T
Accessory
What type of receptors are alpha/beta and
delta/gamma that bind to antigens?
T cell Antigen receptors
What is CD4 and CD8 examples of in terms of T cells?
Accessory molecules
Both CD4 and CD8 share one function of _______
Memory
Which accessory molecules has the following function:
Helper 1, 2, 17
Regulatory
CD4
What accessory molecule has the following function:
Cytotoxic
Regulatory
CD8
How many TCR receptors are there? (They are identical)
30,000
What type of T cells are used for activation of B cells, Cytotoxic cells, and the immune response?
Helper T cells
What type of cells can be referred to as “professional antigen presenting cells”, who present the antigens to helper T cells?
Dendritic cells (APC)
What kind of molecules are the antigens presented to the helper T cell?
MHC molecules
What type of antigen receptors (alpha/beta or delta/gamma) are CD4 and CD8?
alpha/beta
