Cellular Immune 2- Part 1

Question 1

What provides immunity to:
Intracellular bacteria and virus
Fungi
Protozoa
Tumors

Answer 1

Cellular immune response

Question 2

T cells recognize antigen only when it is presented on the ________ of APC by self MHC molecules

Answer 2

Surface

Question 3

Infected cells are killed or are _______ and destroy the intracellular micro-organism

Answer 3

Activated

Question 4

What type of cells mediate the killing and, activated and destruction of intracellular micro-organism?

Answer 4

T cells

Question 5

Endogenous = MHC class _

Answer 5

1

Question 6

Endogenous antigen is first broken down into small peptides and inserted into the antigen binding groove of MHC class _ molecules

Answer 6

1

Question 7

When presented on a cell surface, antigen bound to MHC class 1 molecules triggers a ________ T-cell response

Answer 7

Cytotoxic

Question 8

What type of caspases is activated by multi molecular death complexes?

Answer 8

Initiator- 2,8,9,10,14

Question 9

What type of caspases break down cellular structures?

Answer 9

Effector- 3,6,7

Question 10

What type of caspases is activated by multi molecular inflammasomes?

Answer 10

Inflammatory- 1,4,5,11

Question 11

What is caspases related to?

Answer 11

NK cells

Question 12

What results in clumping of chromatin, blabbing, loss of organelles, nuclear fragmentation?

Answer 12

Apoptosis

Question 13

Cell cooperation in cellular immune response:
What are the 3 major cells?

Answer 13

Dendritic cells
CD4 + T cell
CD8 + T cell

Question 14

Cell cooperation in cellular immune response:
What are the 4 major cytokines?

Answer 14

IL-2 and 12
IFN-y
CCL22

Question 15

Cell cooperation in cellular immune response:
Starts with: dendritic cell + APC on MHC _

Answer 15

1

Question 16

CD__/CD____ is presented on all CD4 + T cell

Answer 16

40/154

Question 17

IL-__ and CCL22 activates dendritic cell and APC on MHC 1 from CD4 + T cells

Answer 17

12