Human Anatomy exam 1 Flashcards
function of kidneys
1.excretions of metabolic wastes 2.maintain water-salt balance& blood volume, pressure 3. maintain acid-base balance 4. production of hormones
secretion of hormones
renin: secretion of aldostrone - reabsorbs sodium ions which help control blood pressure.
Erythropoietin - stimulates the production of rbc
blood supply- renal artery
carries oxygenated blood to kidneys
bs - afferent arterioles
blood to glomerules
bs- efferent arterioles
carry blood away from glomerulus
bs- renal veins
carry away blood filtered by kidneys
the nephron
filtration of blood, reabsorbs filtered substances back into blood, secretion of unwanted substances
nephron structure
bowmans capsule, proximal convoluted tubule, loop of henle, distal convoluted tubule, collecting duct
glomerular filtration
large molecules like blood cells, large proteins remain in the G. 10% of plasma filtered
glomerular filtration rate
volume of liquid that filters into bowmans. average gfr is 125ml/min
influenced by – 1. filtration pressure 2. filtration coefficient 2 components - surface area and permability
autoregulation
of gfr is a control process in which the kidney contains a relatively constant gfr in an event of fluctuations in blood pressure
tubular reabsorption
move substances from tubules back into blood. 180 litres everyday and only 1.4-1.8L excreted.
mainly occurs in the PCT and small amount in DCT. reabsorption mechanisms- active transport, passive movement
why is loop of henle useful
concentrate the filtrate and adjust its composition, longer the loop the more concentrated the filtrate
nutrient transport
if their concentration in the filtrate rises to high t may reach transport maximum or renal threshold = these substances will appear in urine
tubular secretion
movement of molecules from extracellular fluid back into the tubules if they need to be eliminated from the body
aldosterone
regulate sodium & potassium, increses water retention, increase blood pressure
ADH
increasing water absorption in the collecting ducts, controls reabsorption of water, plays key role in homeostasis
excretion
= filtration-reabsoption+ secretion
creatinine
standard test for assesing renal function
insulin
most accurate substance to measure bc it passes through the urine without being reabsorbed
micturition
bladder can expand to 500ml, bladder stores urine until it is released in the process as micturition