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Zak, Heme/Lymph > Hubbard - RBC Disorders > Flashcards

Hubbard - RBC Disorders Flashcards

1
Q

Sx’s = facial rubor, pruritus after bath, hyperviscosity, and increased LAP

A

PCV

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2
Q

PCV is associated w/ what syndrome

A

Budd-Chiari

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3
Q

How is the RI interpreted

A

RI > 2.5% = high RBC destruction

RI < 2.5% = poor RBC production

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4
Q

What is the Tx for PCV

A

Phelbotomy

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5
Q

What mutation is seen in acquired Fe-deficiency anemia

A

nRAMP2 (DCT1)

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6
Q

What infection causes aplastic crisis in pts w/ Sickle Cell

A

Parvovirus

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7
Q

Sx’s = bone pain, dactylitis

A

Sickle Cell

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8
Q

Sickle Cell causes a pt to be at an increased risk for which infection

A

Salmonella

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9
Q

What is the Tx for Warm Ab IgG anemia

A

Steroids

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10
Q

What infection can cause Cold Ab IgA anemia

A

3˚ Syphillis

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11
Q

Sx’s = blackwater fever d/t hemolytic anemia

A

Malaria

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12
Q

Sx’s = Oraya fever d/t infectious adhesion to RBC membranes and causing hemolysis

A

Bartonellosis (Carrions disease)

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13
Q

What morphologic feature will you see in Bartonellosis (Carrions disease)

A

Maltese cross sign

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14
Q

What is the Tx for pts w/ anemia of chronic disease

A

Hgb 10-12 = observation

Hgb < 10 = transfusion

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15
Q

What is a Tx for Sickle Cell

A

Hydroxyurea

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16
Q

Deficiency of porphybolinogen deaminase

A

Acute Intermittent Porphyria

17
Q

What are the common Sx’s of Acute Intermittent Porphyria

A

Colicky Ab pain
Port wine-colored urine
Neuro/Psychiatric issues

18
Q

What is elevated in the urine in pts with Acute Intermittent Porphyria

A

PBG

ALA

19
Q

What is the Tx for Acute Intermittent Porphyria

A

STAT heme

Hydration w/ D5 or D10

20
Q

Deficiency of hepatic uroporphyrinogen decarboxylase

A

Polycythemia Cutanea Tarda

21
Q

What are the common Sx’s of Polycythemia Cutanea Tarda

A

Pseudoscleroderma
Facial pigmentation
Vesicular/ulcerative lesions
Erythema

22
Q

Polycythemia Cutanea Tarda pts have an increased risk of…

A

HCC

23
Q

What is the Tx for Polycythemia Cutanea Tarda

A

Phlebotomy

Zak, Heme/Lymph (15 decks)

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