Description of Diseases Flashcards
Nodules of hypercellularity in germinal centers d/t B-cell hyperproliferation in older adults
Follicular lymphoma
Proliferation of large B-cells in older men
DLBCL
Multiple lymphatic masses with African (jaw) and Sporadic (ab mass) forms
Burkitt lymphoma
CD4 cell neoplasm in pts w/ HTLV-1
Adult T-Cell Leukemia/Lymphoma
Mutations of germinal center B-cells w/ RS cells
HL
B-cell neoplasm in the nervous system of immunosuppressed pts
Primary CNS lymphoma
Accumulation of myeloblasts in BM in adults around 60 yo
AML
Increased proliferation of granulocyte and megakaryocyte progenitor cells in older men
CML
Increased production of lymphoblasts in children
ALL
Abnormal proliferation of mature B-cells in pts > 60 yo
CLL
Abnormal B-cell neoplasm w/ needle-like projections in men > 55 yo
Hairy Cell Leukemia
Inability to cleave vWF causing thrombus formation and subsequent hemolysis of RBCs
Thrombotic Thrombocytopenic Purpura (TTP)
AutoAb mediated destruction of platelets in kids or women > 40 yo
Idiopathic/Immune Thrombocytopenic Purpura (ITP)
Increased platelet number w/ no polycythemia or BM fibrosis in pts > 60 yo
Essential Thrombocytosis
Decreased Factor VIII and prolonged PTT
Hemophilia A (XR)