HTN in pregnancy Flashcards
Onset of hypertension without proteinuria or other systemic findings diagnostic for preeclampsia after week 20 of pregnancy
Systolic BP >140, diastolic BP >90
Gestational hypertension
Pregnancy-specific condition in which hypertension and proteinuria develop after 20 weeks of gestation in a previously normotensive woman
preeclampsia
In the absence of proteinuria, preeclampsia may be defined as hypertension along with the following:
Thrombocytopenia Impaired liver function New development of renal insufficiency Pulmonary edema New-onset cerebral or visual disturbances
Onset of seizure activity or coma in a woman with preeclampsia
No history of preexisting pathology
eclampsia
Women can develop eclampsia…
in the immediate postpartum period OR
50% of eclamptic women develop the condition while pregnant
Hypertension present before pregnancy or diagnosed before week 20 of gestation
chronic hypertension
Chronic hypertension with superimposed preeclampsia
Women with chronic hypertension may acquire preeclampsia or eclampsia
Can be difficult to diagnose
what is the cause of preeclampsia
unknown, many theories
Progressive disorder with placenta as the root cause
Begins to resolve after the placenta has been expelled
Preeclampsia
Vascular remodeling does not occur or only partially develops in women with preeclampsia leading to what
decreased placental perfusion and hypoxia result
what does placental ischemia lead to
endothelial cell dysfunction
what does generalized vasospasm
poor tissue perfusion in all organ systems
Increased peripheral resistance and blood pressure (BP)
Increased endothelial cell permeability
Laboratory diagnosis for a variant of severe preeclampsia that involves hepatic dysfunction
HELLP
breakdown the HELLP components
Hemolysis (H)
Elevated liver enzymes (EL)
Low platelets (LP)
HELLP syndrome occurs in
0.5% to 0.9% of all pregnancies.