HSP Flashcards
1
Q
what infections can cause HSP?
what environmental things?
A
- Group A strep
- mycoplasma
- EBV
- allergens
- pesticides
- cold
- insect bites
- vaccinations
2
Q
what is HSP?
who is the peak prevalence in?
what 4 organs does HSP affect?
A
- IgA mediated autoimmune hypersensitivity vasculitis
- 4-6 year olds
- females and caucasians
- skin
- joints
- kidneys
- gut
3
Q
what is the typical clinical history?
A
- winter months
- preceding URTI
- low grade fever
4
Q
where will they’re rash typically present? what does it look like?
A
- symmetrical, erythematous macular
- back of legs, buttocks, ulnar side of the arm
5
Q
thinking about what organs they affect, what kind of symptoms might they have?
A
- abdo pain, vomiting, bloody diarrhoea
- swollen tender knees and ankles
- nephrotic syndrome
- haematuria, proteinuria
- 2-3% will get intussusception
6
Q
what would you expect in blood results?
A
- elevated IgA levels
- raised WCC wit eosinophilia
7
Q
what is the management of HSP?
A
- self limiting (supportive)
- NSAIDs, unless renal involvement
- steroids, azathioprine, cyclophosphamide may all be beneficial
8
Q
what are the complications of HSP?
A
- dependant on severity of renal involvement (10% have end stage KD)
- MI, pulmonary haemorrhage, pleural effusion, GI bleed
