Hospital Nephrology 2

Question 1

What is the pore size in low flux haemodialysis and what are the cut off points for mw?

Answer 1

1.8nm

3000 - 5000 Da

Question 2

What is kuf?

Answer 2

Movement of water across the membrane when 1mmHg pressure is applied

Question 3

What is the pore size and cut of point for high flux haemodialysis?

Answer 3

3.3nm

30000-50000Da

Question 4

What are long term complications of dialysis?

Answer 4

Amyloidosis
Anaemia 
CVD
Inflammatory reactions 
Lipid profiles 
Vascular disorders

Question 5

What does haemodialfiltration use and how is solute and fluid removed by?

Answer 5

Uses: haemodialyser, dialysate and replacement fluid

Solute: convection and diffusion

Fluid: ultrafiltration

Question 6

What are complications of HD?

Answer 6

Cramps 
Catheter related thrombosis 
Catheter related infections 
Infection 
Nausea and vomiting 
Pruritus 
Anaemia 
Fluid restriction 
Hypotension

Question 7

What are the 2 types of peritoneal dialysis?

Answer 7

CAPD- continuous ambulatory peritoneal dialysis

APD - automated peritoneal dialysis

Question 8

What are the advantages of peritoneal dialysis?

Answer 8

More haemodynamic stability 
Preserves renal function better
Fluid intake and diet less restricted 
Greater flexibility for patient 
Less blood loss and Iron deficiency 
No heparin required

Question 9

What are the disadvantage of PD?

Answer 9

Low efficacy 
Exit site infections 
Protein loss 
Obesity 
Peritonitis 
Duration limited
 hernias 
Iron administration

Question 10

What are the complications of post transplant?

Answer 10

Infective 
Rejection 
ADRs from immunosuppression 
Neoplasia risk 
Post transplant lymphoproliferative disorder 
Skin

Question 11

When should a patient start RRT?

Answer 11

When eGFR is between 5-10 ml/min/1.73m2