Hormones & Immunology in Skin Flashcards

0
Q

bronzing of the skin

A

decreased ACTH

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1
Q

atrophy & striae, purpura, steroid acne, hirsutism, moon facies- all influenced by?

A

Glucocorticoids

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2
Q

Moon facies associated with?

A

Cushing’s disease

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3
Q

growth hormone associated with?

A

epidermal hyperplasia and hyperpigmentation

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4
Q

insulin resistant DM

A

acanthosis nigricans

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5
Q

acanthosis nigricans is?

A

brown, velvety-feeling neck and/or axilla

assoc. w/ DM T2

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6
Q

effect of norepinephrine

A

profuse sweating

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7
Q

hyperthyroidism

A

warm, moist skin

thickened skin on legs (pretibial myxedema)

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8
Q

warm, moist skin

pretibial myxedema

A

hyperthyroidism

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9
Q

dry, cool skin

generalized thickening

A

hypothyroidism

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10
Q

hypothyroidism

A

dry, cool skin

generalized thickening

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11
Q

IgE, mast cells, basophils

A

Type I (immediate)

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12
Q

Type I immunity examples

A

hives, bronchospasm, edema

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13
Q

Type II (cytotoxic)

A

IgG and IgM interact w/ surface antigen and activate complement

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14
Q

Type III (immune complex)

A

antigen-antibody complexes deposited in tissues, causing inflammation

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15
Q

which Types of immunities activate complement?

A

Type II and Type III

16
Q

Type IV (delayed hypersensitivity)

A

cell-mediated immunity. 24-48h after exposure

17
Q

Type IV immunity example

A

poison ivy

18
Q

Type III results in what vascular effect

A

increased vascular permeability