Hormones & Immunology in Skin Flashcards
bronzing of the skin
decreased ACTH
atrophy & striae, purpura, steroid acne, hirsutism, moon facies- all influenced by?
Glucocorticoids
Moon facies associated with?
Cushing’s disease
growth hormone associated with?
epidermal hyperplasia and hyperpigmentation
insulin resistant DM
acanthosis nigricans
acanthosis nigricans is?
brown, velvety-feeling neck and/or axilla
assoc. w/ DM T2
effect of norepinephrine
profuse sweating
hyperthyroidism
warm, moist skin
thickened skin on legs (pretibial myxedema)
warm, moist skin
pretibial myxedema
hyperthyroidism
dry, cool skin
generalized thickening
hypothyroidism
hypothyroidism
dry, cool skin
generalized thickening
IgE, mast cells, basophils
Type I (immediate)
Type I immunity examples
hives, bronchospasm, edema
Type II (cytotoxic)
IgG and IgM interact w/ surface antigen and activate complement
Type III (immune complex)
antigen-antibody complexes deposited in tissues, causing inflammation