AS, CTS et al Flashcards
ankylosing spondylitis pathophysiology
inflammation at tendon/ligament insertion site onto bone —>
ossification happens over time —>
development of syndesmophytes –>
fusion of vertebral bodies
inflammatory disease of the axial skeleton characterized by symmetric sacroiliitis & progressive inflammatory arthritis
Ankylosing spondylitis
presentation: LBP around SI joint area, radiating upwards. Stiffness exacerbated by inactivity, improved w/ moderate activity. Morning back stiffness > 1 hr. Acute anterior uveitis
ankylosing spondylitis
circumcorneal, unilateral uveitis
eye pain, photophobia, blurred vision
associated with which musculoskeletal condition?
ankylosing spondylitis
Shober test (for what and how?)
for ankylosing spondylitis
mark 10 cm above and 5 cm below where iliac crest meets the spine. Pt fwd flexes. Measure distance- should be > 20 cm between the marks
lab findings for ankylosing spondylitis (3)
elevated ESR, CRP
Anemia on CBC for anemia of chronic disease
Increased alkaline phosphatase in 50& due to increased ossification
ankylosing spondylitis tx (primary care) (4)
NSAIDs- Indomethacin (Indocin), Celecoxib (Celebrex)
intra-articular steroids every 3-4 mo.
antidepressants/hypnotics
refer to opthalmology for uveitis
advanced ankylosing spondylitis tx (post-rheumatology referral) (3 groups)
Tumor necrosis factor a-antagonists (Etanercept, infliximab, adalimumab)
Sulfasalazine (Azulfidine) for peripheral arthritis
Biologic agents: MTX, azathioprine
pain, paresthesias, & weakness in the distribution of the median n. in the hand
carpal tunnel syndrome
carpal tunnel syndrome pathophysiology/cause
commonly caused by repetitive overuse
swelling of the synovium and/or thickening of the transverse ligament, leading to nerve compression
concern with acute carpal tunnel?
carpal canal compartment syndrome
chronic carpal tunnel syndrome tx (5)
NSAIDs, corticosteroid injection, splint, PT, surgical release
inflammation of extensor pollicis brevis & abductor pollicus longus tendons of the thumb
DeQuervain Tenosynovitis
either sharp or aching pain at the dorsal aspect of the wrist with referred pain to the thumb and lateral forearm, caused by overuse, repetitive gripping. Weakness of the thumb extension and abduction
DeQuervain Tenosynovitis
how to perform the Finklestein test?
make a fist with the thumb inside, put it into ulnar deviation –> sharp pain indicates DeQuervain’s tenosynovitis