Homeostasis Flashcards
homeostasis definition
maintain variability around a set point
negative feedback
- turns down
- attempts to maintain set point
positive feedback
- turns up
- attempts to amplify the variable
examples of negative feedback
- BP at rest
- Blood glucose
examples of positive feedback
- BP at exercise
- Oxytocin
highly controlled homeostatic variables
- BP
- CO2
- O2
- Blood Glucose
- Core Body Temperature
- pH
- Electrolytes
gain definition
effectiveness of controlling physiological variable
high gain
fast, small response (core body temperature)
low gain
slow, large response (BP)
Order of feedback loop
- Stimulus
- Sensor/Receptor
- Afferent pathway
- Integrating Center
- Efferent Pathway
- Target/Effector
- Response
a-pancreatic cells secrete
glucagon
b-pancreatic cells secrete
insulin, amylin
what does deconditioning (bed rest) do?
causes a low gain system in a normally high gain system, inability to maintain BP with ambulation (orthostatic intolerance)
what does dehydration do?
- volume contraction
- high gain system
- large increase in ADH to reclaim H2O
what does hydration do?
- volume expansion
- low gain system
- dont need to work hard to recover H2O