Homeostasis Flashcards

1
Q

homeostasis definition

A

maintain variability around a set point

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2
Q

negative feedback

A
  • turns down

- attempts to maintain set point

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3
Q

positive feedback

A
  • turns up

- attempts to amplify the variable

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4
Q

examples of negative feedback

A
  • BP at rest

- Blood glucose

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5
Q

examples of positive feedback

A
  • BP at exercise

- Oxytocin

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6
Q

highly controlled homeostatic variables

A
  • BP
  • CO2
  • O2
  • Blood Glucose
  • Core Body Temperature
  • pH
  • Electrolytes
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7
Q

gain definition

A

effectiveness of controlling physiological variable

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8
Q

high gain

A

fast, small response (core body temperature)

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9
Q

low gain

A

slow, large response (BP)

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10
Q

Order of feedback loop

A
  • Stimulus
  • Sensor/Receptor
  • Afferent pathway
  • Integrating Center
  • Efferent Pathway
  • Target/Effector
  • Response
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11
Q

a-pancreatic cells secrete

A

glucagon

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12
Q

b-pancreatic cells secrete

A

insulin, amylin

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13
Q

what does deconditioning (bed rest) do?

A

causes a low gain system in a normally high gain system, inability to maintain BP with ambulation (orthostatic intolerance)

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14
Q

what does dehydration do?

A
  • volume contraction
  • high gain system
  • large increase in ADH to reclaim H2O
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15
Q

what does hydration do?

A
  • volume expansion
  • low gain system
  • dont need to work hard to recover H2O
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16
Q

what kind of feedback is it if compensation fails?

A

positive feedback&raquo_space;> death

17
Q

goal of medical intervention

A
  • keep systems in negative feedback

- avoid viscous cycles (hemorrhage/blood loss)

18
Q

what variable is NOT controlled by homeostasis?

A

HR