HNS42 Orbit Flashcards
***Contents of the orbit
- Eyeball
- 1/5 of orbit - Muscles
- Recti x4
- Oblique x2
- Levator palpebrae superioris
- Superior tarsal muscle (Muller’s muscle) - Nerves
- CN2, 3, 4, 6
- CNV1 (Lacrimal, Frontal, Nasociliary)
- CNV2 (Infraorbital, Zygomatic) - Vessels
- Ophthalmic artery and branches (ICA)
- Infraorbital vessels (ECA —> Maxillary)
- Middle meningeal artery and branches (Maxillary)
- Superior + Inferior Ophthalmic vein - Orbital fat, Reticular tissue, Orbital fascia
- Lacrimal gland + Lacrimal sac
Anatomy of eyeball
Anterior segment:
- Conjunctiva (anterior covering Sclera)
- Iris
- Lens (controlled by Ciliary body)
- Pupil
- Cornea
- Anterior chamber (anterior to iris, drainage of aqueous through trabecular meshwork)
- Ciliary body (production of aqueous —> posterior chamber —> anterior chamber)
- Posterior chamber (behind iris)
Posterior segment:
- Vitreous body
- Macula (concentration of cone cells)
- Retina
- Choroid (pack of blood vessels)
- Optic nerve
***Arterial supply of eyeball
Internal carotid artery —> Ophthalmic artery —>
- Retinal artery
- Posterior ciliary arteries (Long + Short)
- Muscular artery —> Anterior ciliary arteries
Anterior segment:
1. Iris + Ciliary body:
—> **Long Posterior ciliary artery (through choroid) anastomose with **Anterior ciliary artery (through extraocular muscles)
—> Minor arterial arcade + Major arterial arcade (trauma: Hyphema)
- Sclera + Conjuntiva + Iris
—> ***Anterior ciliary artery
Posterior segment:
- Retina —> ***Retinal artery (within RNFL Retina Nerve Fibre Layer)
- Choroid —> **Long (anterior to equator)+ **Short Posterior ciliary artery (posterior to equator)
- ***Dual circulation —> Retina and Choroidal circulations are separate circulations
Central retinal artery
- Supply retina
- Pierce Dural sheath of optic nerve 12 mm behind the globe
- Gives off small meningeal branches to supply Pial sheath of optic nerve
**Clinical relevance: **Central retinal artery occlusion
—> Retinal circulation occluded by emboli
—> Choroidal circulation unaffected
—> **Cherry red spot at fovea (unaffected Choroidal circulation) in middle of **Pale retina (occluded Retinal circulation) (oedematous retina due to ischaemia)
Ciliary arteries
Major blood supply of globe
- Long Posterior ciliary artery
- paired arteries that pierce sclera outside the circle of Zinn and travel forward in suprachoroidal space to **Ciliary body
- gives recurrent branches that supply **Choroid anterior to equator and anastomose with Short Posterior ciliary artery - Short Posterior ciliary artery
- 10-20 branches pierce sclera around optic nerve (i.e. at the back)
- anastomotic circle of Zinn supply optic nerve head (Optic disc)
- supply ***Choroid posterior to equator (posterior 2/3 Choroid) - Anterior ciliary artery
- 7 arteries —> 2 for each **rectus muscle except Lateral Rectus (only 1)
- supply **Sclera + **Conjuntiva + **Iris
Anterior segment
- Long Posterior ciliary artery
- Anterior ciliary artery
—> Iris + Ciliary body
- Iris vessels: Non-fenestrated (endothelial tight junctions)
- Ciliary body vessels: ***Fenestrated (NO tight junctions) —> allow production of aqueous humour
- ***Blood aqueous barrier (tight junctions in ciliary epithelium + iris endothelium to prevent substances going into eye)
Posterior segment
- Retina: ***Retinal artery
- 10 layers:
—> Inner 2/3: Central retinal artery
—> Outer 1/3 (beyond Outer Plexiform Layer): Watershed area (diffusion to get nutrients) —> Foveal avascular zone: absent capillaries over fovea (highest concentration of cone cells) —> age-related macular degeneration - Choroid: ***Long + Short Posterior ciliary artery
- Short Posterior ciliary artery: posterior to equator
- Long Posterior ciliary artery: anterior to equator
- **Blood retinal barrier:
- Tight junction between Retinal Pigment Epithelium
- Separate retinal circulation from choroidal circulation —> prevent substances going into eye
***Blood aqueous barrier + Blood retinal barrier
- **Blood aqueous barrier:
- Tight junctions in ciliary epithelium + iris endothelium to prevent substances going into eye
- **Blood retinal barrier:
- Tight junction between RPE (retinal pigment epithelium) of retina
- Separate retinal circulation from choroidal circulation —> prevent substances going into eye
- Immune privileged site: Part of the brain but exposed to outside
***Venous drainage of eye
- Retina: ***Central retinal vein
- Choroid: 4 Vortex veins (2 superior, 2 inferior)
- exit eyeball posterior to equator
- **Superior Vortex veins —> Superior Ophthalmic vein / Cavernous sinus
- **Inferior Vortex veins —> Inferior Ophthalmic venous plexus / Cavernous sinus
- Central retinal vein
- Supraorbital vein
- Facial vein
Clinical relevance:
- Cavernous sinus thrombosis (infection of orbit —> proptosis)
- Central retinal vein occlusion (haemorrhage of retina due to blockage of drainage)
***Orbit
4 walls from 7 bones:
- Ethmoid
- Frontal
- Lacrimal
- Maxillary
- Palatine
- Sphenoid
- Zygomatic
Anatomical space boundary:
- Superior: Anterior cranial fossa
- Inferior: Maxillary sinus
- Medial: Nasal cavity + Ethmoidal air cells
- Lateral: Middle cranial fossa
Superior wall
Triangular shape
Bones:
- Frontal bone (anterior)
- Lesser wing of sphenoid (posterior)
Relations: - Above: —> Frontal lobe + meninges - Below: —> Periorbita, Frontal nerve, Trochlear nerve, LPS, SR, SO, Lacrimal gland
Anterior + Posterior Ethmoidal canals: present at junction of roof + medial wall
Inferior wall / Floor
Triangular shape, Shortest
Bones: 1. Maxillary bone (medial) 2. Zygomatic bone (lateral) 3. Palatine bone (posterior) —> ***Inferior orbital fissure separate posterior part of floor from lateral wall
Infraorbital nerve + vessels:
- Inferior orbital fissure —> groove —> canal —> Infraorbital foramen
Relations: - Below: —> Mamillary + Palatine air sinus - Above: —> Inferior oblique muscle + Rectus muscle + Nerve to Inferior oblique muscle
Clinical relevance:
- Orbital blow-out fracture —> floor fracture —> can damage Infraorbital nerve
Medial wall
Quadrangular shape
Bones:
- Frontal process of maxilla
- Lacrimal bone
- Orbital plate of ethmoid
- Sphenoid body
Lacrimal fossa (Maxilla + Lacrimal bone):
- Anterior lacrimal crest = Maxilla
- Posterior lacrimal crest = Lacrimal bone
Relations: - Medial: —> Anterior, Middle, Posterior Ethmoid sinus —> Middle meatus - Orbital surface related to Superior oblique + Medial rectus: —> Anterior + Posterior ethmoid nerve —> Intratrochlea nerve —> Terminal branch of ophthalmic artery
Lateral wall
Triangular shape
Bones:
- Zygomatic bone (anterior)
- Greater wing of sphenoid (posterior)
Relations: - Lateral: —> Temporal fossa (anterior) —> Middle cranial fossa (posterior) - Medial: —> Lateral Rectus muscle —> Lacrimal nerves + vessels —> Zygomatic nerves and their communication
Apex of orbit
- Superior orbital fissure
- CNV1 (Lacrimal + Frontal)
- CN4 - Inferior orbital fissure
- CNV2 (Zygomatic)
- Infraorbital nerve - Optic canal
- Optic nerve - Annulus of Zinn (origin of most extraocular muscles)
- CN3 (superior + inferior)
- CNV1 (Nasociliary)
- CN6
Thyroid eye disease
Inflammation of ocular muscles —> Enlarged
- Proptosis + Diplopia
- Compress CN2 at apex —> Vision loss
Arterial supply of orbit
Internal carotid artery —> Ophthalmic artery —>
- Anterior + Posterior Ethmoidal artery
- Supratrochlear artery
- Supraorbital artery
- Lacrimal artery
Venous drainage of orbit
Posterior:
- Cavernous sinus + Deep facial vein
Anteromedial:
- Ophthalmic vein
- Angular vein
Anterolateral:
- Superficial temporal vein
***Innervation of orbit
CNV1 —> Medial part:
- Supraorbital nerve
- Supratrochlear nerve
CNV2 —> Lateral + Inferior part:
- Infraorbital nerve
- Zygomatic nerve
Ocular alignment of extraocular muscles
Globe not in parallel with axis of orbit
Synchronous ocular movement is performed by 6 extraocular muscles in each orbit (Rectus x4, Obliques x2)
—> Muscles controlled by brainstem via CN3, 4, 6
Rectus muscle
Pierce Tenon’s capsule —> insert into Sclera in front of equator
Blood supply:
Anterior ciliary artery
- 7 arteries —> 2 for each ***rectus muscle except Lateral rectus (only 1)
1. Medial muscular artery —> Medial, Inferior rectus
2. Lateral muscular artery —> Lateral, Superior rectus
Nerve:
- CN3 —> Medial, Superior, Inferior rectus
- CN6 —> Lateral rectus
(Superior rectus: Complex with Levator palpebrae superioris
—> allow retraction of eyelid when eye elevate
Inferior rectus: Complex with Lower lid retractor)
Superior oblique + Inferior oblique muscles
Blood supply:
- Medial muscular artery: Inferior oblique
- Lateral muscular artery: Superior oblique
Nerve supply:
- CN4: Superior oblique (***Contralateral)
- CN3: Inferior oblique
Inferior oblique: only muscle NOT from Annulus of Zinn, originate from Anterior orbit!!!
Actions of extraocular muscles
Medial rectus: Adduction (向內望)
Lateral rectus: Abduction (向外望)
Superior rectus: Elevation (+ adduction, intorsion)
Inferior rectus: Depression (+ adduction, extorsion)
Superior oblique: Intorsion (向內擰) (+ abduction, depression)
Inferior oblique: Extorsion (向外擰) (+ abduction, elevation)