HLTH 237 Ch. 8,9,12 Flashcards
What is the primary effect of depressants on the central and peripheral nervous systems?
They slow down the CNS and PNS, reducing heart rate, respiratory rate, and reaction time.
What are the three main categories of depressants discussed in Chapter 8?
Barbiturates and benzodiazepines (medically useful but dangerous), inhalants and solvents (used recreationally), and alcohol (culturally acceptable).
What neurotransmitter do barbiturates and benzodiazepines primarily affect?
GABA (Gamma-Aminobutyric Acid)
What are the two primary effects of barbiturates?
Sedative (relieves anxiety) and hypnotic (induces sleep).
Why are barbiturates considered highly dangerous in terms of withdrawal?
They have the most severe withdrawal symptoms of all psychoactive drugs, with a risk of fatality from immediate withdrawal or overdose.
Name three examples of barbiturates.
Pentobarbital, Phenobarbital, Primidone.
Why were non-barbiturate sedative-hypnotics introduced in 1954?
They were marketed as a “safe, non-addictive” alternative to barbiturates for sleep.
How do benzodiazepines differ from barbiturates?
They were designed to be a safer alternative but still cause dependence within four weeks.
What are the dangers associated with non-barbiturate sedative-hypnotics?
They cause rapid tolerance, physical dependence, disruption of REM sleep, and life-threatening withdrawal.
What happens when benzodiazepines are mixed with alcohol?
They can cause rapid intoxication, temporary blackouts, and memory impairment.
Give three examples of benzodiazepines
Xanax (alprazolam), Valium (diazepam), Ativan (lorazepam)
What are the two major categories of inhalants?
- Organic solvents (gasoline, glue)
- anesthetic inhalants (ether, nitrous oxide).
What are “Z-drugs,” and how do they differ from benzodiazepines?
Z-drugs (e.g., Ambien, Lunesta) were developed for insomnia and have a lower risk of dependence and withdrawal.
Why are inhalants particularly dangerous for young people?
hey are readily available and can cause permanent brain damage.
Why is alcohol considered both a depressant and a social enhancer?
It reduces inhibition and impairs judgment, but its effects vary depending on social setting and expectations.
What are some of the historical origins of alcohol?
Mead (8000 BCE), beer and berry wine (6400 BCE), and grape wine (300-400 BCE).
What is gamma-hydroxybutyrate (GHB), and why is it dangerous?
It is a depressant often used recreationally; when combined with alcohol, it can cause memory loss and unconsciousness.
What percentage of road traffic deaths in Canada are linked to alcohol impairment?
33%
What is the primary cause of a hangover?
What are some long-term health effects of alcohol use?
What are some long-term health effects of alcohol use?
Damage to the brain, liver, cardiovascular system, and increased risk of cancer and developmental disabilities (e.g., fetal alcohol spectrum disorder).
What is the primary source of natural opioids?
The opium poppy plant
What makes opioids different from other psychoactive substances?
Their strong ability to produce physical and psychological dependence.
What are the three major effects of opioids on the body?
Pain relief, suppression of the gastrointestinal tract, and cough suppression.
What are the three main categories of opioids?
Natural, semi-synthetic, and synthetic.